HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus.

HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus.

Endoplasmic reticulum (ER) stress is a condition in which the protein folding capacity of the ER becomes overwhelmed by an increased demand for secretion or by exposure to compounds that disrupt ER homeostasis. In yeast and other fungi, the accumulation of unfolded proteins is detected by the ER-tra...

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Détails bibliographiques
Auteurs principaux: Xizhi Feng, Karthik Krishnan, Daryl L Richie, Vishukumar Aimanianda, Lukas Hartl, Nora Grahl, Margaret V Powers-Fletcher, Minlu Zhang, Kevin K Fuller, William C Nierman, Long Jason Lu, Jean-Paul Latgé, Laura Woollett, Simon L Newman, Robert A Cramer, Judith C Rhodes, David S Askew
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
Sujets:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Accès en ligne:https://doaj.org/article/e8921120d708438bbfb7eba100185cce
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Internet

https://doaj.org/article/e8921120d708438bbfb7eba100185cce

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