Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network

Alignment or anisotropic organisation within and between cells enables biological function but is challenging to engineer. Here, the authors align collagen fibres in a pre-strained polydimethylsiloxane mould to generate a 3D scaffold that guides hippocampal neuron axon growth to form CA3–CA1 neural...

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Autores principales:	So Hyun Kim, Sun-Kyoung Im, Soo-Jin Oh, Sohyeon Jeong, Eui-Sung Yoon, C. Justin Lee, Nakwon Choi, Eun-Mi Hur
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e89794de513e40d5b0d47535845a1b69
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spelling	oai:doaj.org-article:e89794de513e40d5b0d47535845a1b692021-12-02T17:06:00ZAnisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network10.1038/ncomms143462041-1723https://doaj.org/article/e89794de513e40d5b0d47535845a1b692017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14346https://doaj.org/toc/2041-1723Alignment or anisotropic organisation within and between cells enables biological function but is challenging to engineer. Here, the authors align collagen fibres in a pre-strained polydimethylsiloxane mould to generate a 3D scaffold that guides hippocampal neuron axon growth to form CA3–CA1 neural circuits.So Hyun KimSun-Kyoung ImSoo-Jin OhSohyeon JeongEui-Sung YoonC. Justin LeeNakwon ChoiEun-Mi HurNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q So Hyun Kim Sun-Kyoung Im Soo-Jin Oh Sohyeon Jeong Eui-Sung Yoon C. Justin Lee Nakwon Choi Eun-Mi Hur Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network
description	Alignment or anisotropic organisation within and between cells enables biological function but is challenging to engineer. Here, the authors align collagen fibres in a pre-strained polydimethylsiloxane mould to generate a 3D scaffold that guides hippocampal neuron axon growth to form CA3–CA1 neural circuits.
format	article
author	So Hyun Kim Sun-Kyoung Im Soo-Jin Oh Sohyeon Jeong Eui-Sung Yoon C. Justin Lee Nakwon Choi Eun-Mi Hur
author_facet	So Hyun Kim Sun-Kyoung Im Soo-Jin Oh Sohyeon Jeong Eui-Sung Yoon C. Justin Lee Nakwon Choi Eun-Mi Hur
author_sort	So Hyun Kim
title	Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network
title_short	Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network
title_full	Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network
title_fullStr	Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network
title_full_unstemmed	Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network
title_sort	anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e89794de513e40d5b0d47535845a1b69
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Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network

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