Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases

Kei Fukuda et al. show that the formation of chromatin domains marked by dimethylated H3K9 is functionally linked to the 3D organization of the genome. These findings suggest that H3K9 methyltransferases play an important role in maintaining genome organization in more transcriptionally inactive com...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kei Fukuda, Chikako Shimura, Hisashi Miura, Akie Tanigawa, Takehiro Suzuki, Naoshi Dohmae, Ichiro Hiratani, Yoichi Shinkai
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/e89beff64c854c29ab9276b1ff88ac50
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e89beff64c854c29ab9276b1ff88ac50
record_format	dspace
spelling	oai:doaj.org-article:e89beff64c854c29ab9276b1ff88ac502021-12-02T15:43:08ZRegulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases10.1038/s42003-021-02089-y2399-3642https://doaj.org/article/e89beff64c854c29ab9276b1ff88ac502021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02089-yhttps://doaj.org/toc/2399-3642Kei Fukuda et al. show that the formation of chromatin domains marked by dimethylated H3K9 is functionally linked to the 3D organization of the genome. These findings suggest that H3K9 methyltransferases play an important role in maintaining genome organization in more transcriptionally inactive compartments.Kei FukudaChikako ShimuraHisashi MiuraAkie TanigawaTakehiro SuzukiNaoshi DohmaeIchiro HirataniYoichi ShinkaiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Kei Fukuda Chikako Shimura Hisashi Miura Akie Tanigawa Takehiro Suzuki Naoshi Dohmae Ichiro Hiratani Yoichi Shinkai Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases
description	Kei Fukuda et al. show that the formation of chromatin domains marked by dimethylated H3K9 is functionally linked to the 3D organization of the genome. These findings suggest that H3K9 methyltransferases play an important role in maintaining genome organization in more transcriptionally inactive compartments.
format	article
author	Kei Fukuda Chikako Shimura Hisashi Miura Akie Tanigawa Takehiro Suzuki Naoshi Dohmae Ichiro Hiratani Yoichi Shinkai
author_facet	Kei Fukuda Chikako Shimura Hisashi Miura Akie Tanigawa Takehiro Suzuki Naoshi Dohmae Ichiro Hiratani Yoichi Shinkai
author_sort	Kei Fukuda
title	Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases
title_short	Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases
title_full	Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases
title_fullStr	Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases
title_full_unstemmed	Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases
title_sort	regulation of mammalian 3d genome organization and histone h3k9 dimethylation by h3k9 methyltransferases
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e89beff64c854c29ab9276b1ff88ac50
work_keys_str_mv	AT keifukuda regulationofmammalian3dgenomeorganizationandhistoneh3k9dimethylationbyh3k9methyltransferases AT chikakoshimura regulationofmammalian3dgenomeorganizationandhistoneh3k9dimethylationbyh3k9methyltransferases AT hisashimiura regulationofmammalian3dgenomeorganizationandhistoneh3k9dimethylationbyh3k9methyltransferases AT akietanigawa regulationofmammalian3dgenomeorganizationandhistoneh3k9dimethylationbyh3k9methyltransferases AT takehirosuzuki regulationofmammalian3dgenomeorganizationandhistoneh3k9dimethylationbyh3k9methyltransferases AT naoshidohmae regulationofmammalian3dgenomeorganizationandhistoneh3k9dimethylationbyh3k9methyltransferases AT ichirohiratani regulationofmammalian3dgenomeorganizationandhistoneh3k9dimethylationbyh3k9methyltransferases AT yoichishinkai regulationofmammalian3dgenomeorganizationandhistoneh3k9dimethylationbyh3k9methyltransferases
_version_	1718385842739740672

Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases

Ejemplares similares