Malfunctioning CD106-positive, short-term hematopoietic stem cells trigger diabetic neuropathy in mice by cell fusion
Katagi et al. show that abnormal bone marrow-derived cells originated from hematopoietic stem cells (CD106-positive short-term HSCs) aberrantly fuse with neurons to develop diabetic neuropathy. This study suggests that the pathological abnormality is memorized in the bone marrow and that it cannot b...
Saved in:
Main Authors: | Miwako Katagi, Tomoya Terashima, Natsuko Ohashi, Yuki Nakae, Akane Yamada, Takahiko Nakagawa, Itsuko Miyazawa, Hiroshi Maegawa, Junko Okano, Yoshihisa Suzuki, Kazunori Fujino, Yutaka Eguchi, Hideto Kojima |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/e89bf4e21fc54a66a503dcaba1d6baae |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
GLT1 gene delivery based on bone marrow-derived cells ameliorates motor function and survival in a mouse model of ALS
by: Natsuko Ohashi, et al.
Published: (2021) -
A novel role for bone marrow-derived cells to recover damaged keratinocytes from radiation-induced injury
by: Junko Okano, et al.
Published: (2021) -
Shunt malfunction and endoscopy
Published: (2021) -
Gene therapy for neuropathic pain by silencing of TNF-α expression with lentiviral vectors targeting the dorsal root ganglion in mice.
by: Nobuhiro Ogawa, et al.
Published: (2014) -
Acta No. 106
by: Banco Central de Chile
Published: (2019)