Genetic Screen in <named-content content-type="genus-species">Chlamydia muridarum</named-content> Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture

Genetic Screen in <named-content content-type="genus-species">Chlamydia muridarum</named-content> Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture

ABSTRACT Interferon-regulated immune defenses protect mammals from pathogenically diverse obligate intracellular bacterial pathogens of the genus Chlamydia. Interferon gamma (IFN-γ) is especially important in controlling the virulence of Chlamydia species and thus impacts the modeling of human chlam...

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Autores principales: Amanda M. Giebel, Shuai Hu, Krithika Rajaram, Ryan Finethy, Evelyn Toh, Julie A. Brothwell, Sandra G. Morrison, Robert J. Suchland, Barry D. Stein, Jörn Coers, Richard P. Morrison, David E. Nelson
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Chlamydia
host-pathogen interactions
interferon-stimulated genes
intracellular pathogens
molecular genetics
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/e8a90bbcb71f4e98a83cb61cb313a9e4
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