Hyaluronidase Impairs Neutrophil Function and Promotes Group B <i>Streptococcus</i> Invasion and Preterm Labor in Nonhuman Primates

Group B streptococci (GBS) are bacteria that commonly reside in the female lower genital tract as asymptomatic members of the microbiota. However, during pregnancy, GBS can infect tissues at the maternal-fetal interface, leading to preterm birth, stillbirth, or fetal injury.

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Autores principales: Michelle Coleman, Blair Armistead, Austyn Orvis, Phoenicia Quach, Alyssa Brokaw, Claire Gendrin, Kavita Sharma, Jason Ogle, Sean Merillat, Matthew Dacanay, Tsung-Yen Wu, Jeff Munson, Audrey Baldessari, Jay Vornhagen, Anna Furuta, Shayla Nguyen, Kristina M. Adams Waldorf, Lakshmi Rajagopal
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/e8b9aaec47134d77a586d9f927ccda52
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spelling oai:doaj.org-article:e8b9aaec47134d77a586d9f927ccda522021-11-03T18:15:37Z Hyaluronidase Impairs Neutrophil Function and Promotes Group B <i>Streptococcus</i> Invasion and Preterm Labor in Nonhuman Primates 2161-21292150-751110.1128/mBio.03115-20https://doaj.org/article/e8b9aaec47134d77a586d9f927ccda522021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03115-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 Group B streptococci (GBS) are bacteria that commonly reside in the female lower genital tract as asymptomatic members of the microbiota. However, during pregnancy, GBS can infect tissues at the maternal-fetal interface, leading to preterm birth, stillbirth, or fetal injury.Michelle ColemanBlair ArmisteadAustyn OrvisPhoenicia QuachAlyssa BrokawClaire GendrinKavita SharmaJason OgleSean MerillatMatthew DacanayTsung-Yen WuJeff MunsonAudrey BaldessariJay VornhagenAnna FurutaShayla NguyenKristina M. Adams WaldorfLakshmi RajagopalAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Michelle Coleman
Blair Armistead
Austyn Orvis
Phoenicia Quach
Alyssa Brokaw
Claire Gendrin
Kavita Sharma
Jason Ogle
Sean Merillat
Matthew Dacanay
Tsung-Yen Wu
Jeff Munson
Audrey Baldessari
Jay Vornhagen
Anna Furuta
Shayla Nguyen
Kristina M. Adams Waldorf
Lakshmi Rajagopal
Hyaluronidase Impairs Neutrophil Function and Promotes Group B <i>Streptococcus</i> Invasion and Preterm Labor in Nonhuman Primates
description Group B streptococci (GBS) are bacteria that commonly reside in the female lower genital tract as asymptomatic members of the microbiota. However, during pregnancy, GBS can infect tissues at the maternal-fetal interface, leading to preterm birth, stillbirth, or fetal injury.
format article
author Michelle Coleman
Blair Armistead
Austyn Orvis
Phoenicia Quach
Alyssa Brokaw
Claire Gendrin
Kavita Sharma
Jason Ogle
Sean Merillat
Matthew Dacanay
Tsung-Yen Wu
Jeff Munson
Audrey Baldessari
Jay Vornhagen
Anna Furuta
Shayla Nguyen
Kristina M. Adams Waldorf
Lakshmi Rajagopal
author_facet Michelle Coleman
Blair Armistead
Austyn Orvis
Phoenicia Quach
Alyssa Brokaw
Claire Gendrin
Kavita Sharma
Jason Ogle
Sean Merillat
Matthew Dacanay
Tsung-Yen Wu
Jeff Munson
Audrey Baldessari
Jay Vornhagen
Anna Furuta
Shayla Nguyen
Kristina M. Adams Waldorf
Lakshmi Rajagopal
author_sort Michelle Coleman
title Hyaluronidase Impairs Neutrophil Function and Promotes Group B <i>Streptococcus</i> Invasion and Preterm Labor in Nonhuman Primates
title_short Hyaluronidase Impairs Neutrophil Function and Promotes Group B <i>Streptococcus</i> Invasion and Preterm Labor in Nonhuman Primates
title_full Hyaluronidase Impairs Neutrophil Function and Promotes Group B <i>Streptococcus</i> Invasion and Preterm Labor in Nonhuman Primates
title_fullStr Hyaluronidase Impairs Neutrophil Function and Promotes Group B <i>Streptococcus</i> Invasion and Preterm Labor in Nonhuman Primates
title_full_unstemmed Hyaluronidase Impairs Neutrophil Function and Promotes Group B <i>Streptococcus</i> Invasion and Preterm Labor in Nonhuman Primates
title_sort hyaluronidase impairs neutrophil function and promotes group b <i>streptococcus</i> invasion and preterm labor in nonhuman primates
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/e8b9aaec47134d77a586d9f927ccda52
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