Evaluation of The Role of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia

Background: Androgenetic alopecia [AGA] one of the common scalp hair loss disorders affecting males. Androgenetic alopecia is characterized by progressive miniaturization of hair follicles in the scalp and gradual transformation of terminal hairs into vellus hairs leading to progressive decrease in...

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Autores principales: Hebat-Allah Elsherbeny, Hassan Abo Khodier Mohamed, Mohamed Shokry Zaky
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Lenguaje:EN
Publicado: Al-Azhar University, Faculty of Medicine (Damietta) 2020
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Acceso en línea:https://doaj.org/article/e8ba9485028548268571ddc81255a811
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spelling oai:doaj.org-article:e8ba9485028548268571ddc81255a8112021-12-02T10:38:22ZEvaluation of The Role of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia2636-41742682-378010.21608/ijma.2020.34317.1142https://doaj.org/article/e8ba9485028548268571ddc81255a8112020-10-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_107623_5f3378871b69b82ae166531224159fd8.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Androgenetic alopecia [AGA] one of the common scalp hair loss disorders affecting males. Androgenetic alopecia is characterized by progressive miniaturization of hair follicles in the scalp and gradual transformation of terminal hairs into vellus hairs leading to progressive decrease in hair density. The pattern of loss follows the scale developed by Hamilton and later extended by Norwood. Aim of Work: Evaluation of the efficacy of topical cetirizine 1% for the treatment of androgenetic alopecia in male patients. Patients and methods: This case-controlled study included 30 male patients treated by topical cetirizine1%and 30 male patients as a control group treated by placebo for 6 months recruited from dermatology outpatient clinic of Damietta Hospital and Al-Sarou hospital during the period from September 2018 to August 2019. For each patient, the trichoscopic evaluation was performed before the beginning of treatment and after 6 months of treatment. Results: Treatment with topical cetirizine 1% in male patients with AGA showed that according to number of new up growing hairs, the majority [56.7%] of cases had no new growing hair, 20.0%, 16.7% &6.7% had one, two and three new hair respectively. On the other hands, all control had no new hair after 6 months of treatment. Conclusion: Topical cetirizine is effective in the treatment of Androgenetic alopecia in men.Hebat-Allah ElsherbenyHassan Abo Khodier MohamedMohamed Shokry ZakyAl-Azhar University, Faculty of Medicine (Damietta)articlealopeciaandrogeneticcetirizinemaleprostaglandinsMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 4, Pp 793-797 (2020)
institution DOAJ
collection DOAJ
language EN
topic alopecia
androgenetic
cetirizine
male
prostaglandins
Medicine (General)
R5-920
spellingShingle alopecia
androgenetic
cetirizine
male
prostaglandins
Medicine (General)
R5-920
Hebat-Allah Elsherbeny
Hassan Abo Khodier Mohamed
Mohamed Shokry Zaky
Evaluation of The Role of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia
description Background: Androgenetic alopecia [AGA] one of the common scalp hair loss disorders affecting males. Androgenetic alopecia is characterized by progressive miniaturization of hair follicles in the scalp and gradual transformation of terminal hairs into vellus hairs leading to progressive decrease in hair density. The pattern of loss follows the scale developed by Hamilton and later extended by Norwood. Aim of Work: Evaluation of the efficacy of topical cetirizine 1% for the treatment of androgenetic alopecia in male patients. Patients and methods: This case-controlled study included 30 male patients treated by topical cetirizine1%and 30 male patients as a control group treated by placebo for 6 months recruited from dermatology outpatient clinic of Damietta Hospital and Al-Sarou hospital during the period from September 2018 to August 2019. For each patient, the trichoscopic evaluation was performed before the beginning of treatment and after 6 months of treatment. Results: Treatment with topical cetirizine 1% in male patients with AGA showed that according to number of new up growing hairs, the majority [56.7%] of cases had no new growing hair, 20.0%, 16.7% &6.7% had one, two and three new hair respectively. On the other hands, all control had no new hair after 6 months of treatment. Conclusion: Topical cetirizine is effective in the treatment of Androgenetic alopecia in men.
format article
author Hebat-Allah Elsherbeny
Hassan Abo Khodier Mohamed
Mohamed Shokry Zaky
author_facet Hebat-Allah Elsherbeny
Hassan Abo Khodier Mohamed
Mohamed Shokry Zaky
author_sort Hebat-Allah Elsherbeny
title Evaluation of The Role of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia
title_short Evaluation of The Role of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia
title_full Evaluation of The Role of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia
title_fullStr Evaluation of The Role of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia
title_full_unstemmed Evaluation of The Role of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia
title_sort evaluation of the role of topical cetirizine 1% in treatment of male androgenetic alopecia
publisher Al-Azhar University, Faculty of Medicine (Damietta)
publishDate 2020
url https://doaj.org/article/e8ba9485028548268571ddc81255a811
work_keys_str_mv AT hebatallahelsherbeny evaluationoftheroleoftopicalcetirizine1intreatmentofmaleandrogeneticalopecia
AT hassanabokhodiermohamed evaluationoftheroleoftopicalcetirizine1intreatmentofmaleandrogeneticalopecia
AT mohamedshokryzaky evaluationoftheroleoftopicalcetirizine1intreatmentofmaleandrogeneticalopecia
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