Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes

Benign prostatic hyperplasia (BPH) is one of the most common diseases affecting aging men with limited therapeutic options. In this study, the authors describe the molecular characterization of BPH performing genomic, transcriptomic and epigenetic analysis of 18 BPH cases.

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Autores principales:	Deli Liu, Jonathan E. Shoag, Daniel Poliak, Ramy S. Goueli, Vaishali Ravikumar, David Redmond, Aram Vosoughi, Jacqueline Fontugne, Heng Pan, Daniel Lee, Domonique Thomas, Keyan Salari, Zongwei Wang, Alessandro Romanel, Alexis Te, Richard Lee, Bilal Chughtai, Aria F. Olumi, Juan Miguel Mosquera, Francesca Demichelis, Olivier Elemento, Mark A. Rubin, Andrea Sboner, Christopher E. Barbieri
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e8baf4a938944f0fbc66a64df0469d3e
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spelling	oai:doaj.org-article:e8baf4a938944f0fbc66a64df0469d3e2021-12-02T14:41:04ZIntegrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes10.1038/s41467-020-15913-62041-1723https://doaj.org/article/e8baf4a938944f0fbc66a64df0469d3e2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15913-6https://doaj.org/toc/2041-1723Benign prostatic hyperplasia (BPH) is one of the most common diseases affecting aging men with limited therapeutic options. In this study, the authors describe the molecular characterization of BPH performing genomic, transcriptomic and epigenetic analysis of 18 BPH cases.Deli LiuJonathan E. ShoagDaniel PoliakRamy S. GoueliVaishali RavikumarDavid RedmondAram VosoughiJacqueline FontugneHeng PanDaniel LeeDomonique ThomasKeyan SalariZongwei WangAlessandro RomanelAlexis TeRichard LeeBilal ChughtaiAria F. OlumiJuan Miguel MosqueraFrancesca DemichelisOlivier ElementoMark A. RubinAndrea SbonerChristopher E. BarbieriNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Deli Liu Jonathan E. Shoag Daniel Poliak Ramy S. Goueli Vaishali Ravikumar David Redmond Aram Vosoughi Jacqueline Fontugne Heng Pan Daniel Lee Domonique Thomas Keyan Salari Zongwei Wang Alessandro Romanel Alexis Te Richard Lee Bilal Chughtai Aria F. Olumi Juan Miguel Mosquera Francesca Demichelis Olivier Elemento Mark A. Rubin Andrea Sboner Christopher E. Barbieri Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
description	Benign prostatic hyperplasia (BPH) is one of the most common diseases affecting aging men with limited therapeutic options. In this study, the authors describe the molecular characterization of BPH performing genomic, transcriptomic and epigenetic analysis of 18 BPH cases.
format	article
author	Deli Liu Jonathan E. Shoag Daniel Poliak Ramy S. Goueli Vaishali Ravikumar David Redmond Aram Vosoughi Jacqueline Fontugne Heng Pan Daniel Lee Domonique Thomas Keyan Salari Zongwei Wang Alessandro Romanel Alexis Te Richard Lee Bilal Chughtai Aria F. Olumi Juan Miguel Mosquera Francesca Demichelis Olivier Elemento Mark A. Rubin Andrea Sboner Christopher E. Barbieri
author_facet	Deli Liu Jonathan E. Shoag Daniel Poliak Ramy S. Goueli Vaishali Ravikumar David Redmond Aram Vosoughi Jacqueline Fontugne Heng Pan Daniel Lee Domonique Thomas Keyan Salari Zongwei Wang Alessandro Romanel Alexis Te Richard Lee Bilal Chughtai Aria F. Olumi Juan Miguel Mosquera Francesca Demichelis Olivier Elemento Mark A. Rubin Andrea Sboner Christopher E. Barbieri
author_sort	Deli Liu
title	Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
title_short	Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
title_full	Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
title_fullStr	Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
title_full_unstemmed	Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
title_sort	integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e8baf4a938944f0fbc66a64df0469d3e
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Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes

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