An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics
Aging impacts lung functionality and makes it more susceptible to chronic diseases. Combining proteomics and single cell transcriptomics, the authors chart molecular and cellular changes in the aging mouse lung, discover aging hallmarks, and predict the cellular sources of regulated proteins.
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Nature Portfolio
2019
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oai:doaj.org-article:e8bbc178370d42f0a7884140d62b6b592021-12-02T16:50:58ZAn atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics10.1038/s41467-019-08831-92041-1723https://doaj.org/article/e8bbc178370d42f0a7884140d62b6b592019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08831-9https://doaj.org/toc/2041-1723Aging impacts lung functionality and makes it more susceptible to chronic diseases. Combining proteomics and single cell transcriptomics, the authors chart molecular and cellular changes in the aging mouse lung, discover aging hallmarks, and predict the cellular sources of regulated proteins.Ilias AngelidisLukas M. SimonIsis E. FernandezMaximilian StrunzChristoph H. MayrFlavia R. GreiffoGeorge TsitsiridisMeshal AnsariElisabeth GrafTim-Matthias StromMonica NagendranTushar DesaiOliver EickelbergMatthias MannFabian J. TheisHerbert B. SchillerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Ilias Angelidis Lukas M. Simon Isis E. Fernandez Maximilian Strunz Christoph H. Mayr Flavia R. Greiffo George Tsitsiridis Meshal Ansari Elisabeth Graf Tim-Matthias Strom Monica Nagendran Tushar Desai Oliver Eickelberg Matthias Mann Fabian J. Theis Herbert B. Schiller An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics |
| description |
Aging impacts lung functionality and makes it more susceptible to chronic diseases. Combining proteomics and single cell transcriptomics, the authors chart molecular and cellular changes in the aging mouse lung, discover aging hallmarks, and predict the cellular sources of regulated proteins. |
| format |
article |
| author |
Ilias Angelidis Lukas M. Simon Isis E. Fernandez Maximilian Strunz Christoph H. Mayr Flavia R. Greiffo George Tsitsiridis Meshal Ansari Elisabeth Graf Tim-Matthias Strom Monica Nagendran Tushar Desai Oliver Eickelberg Matthias Mann Fabian J. Theis Herbert B. Schiller |
| author_facet |
Ilias Angelidis Lukas M. Simon Isis E. Fernandez Maximilian Strunz Christoph H. Mayr Flavia R. Greiffo George Tsitsiridis Meshal Ansari Elisabeth Graf Tim-Matthias Strom Monica Nagendran Tushar Desai Oliver Eickelberg Matthias Mann Fabian J. Theis Herbert B. Schiller |
| author_sort |
Ilias Angelidis |
| title |
An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics |
| title_short |
An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics |
| title_full |
An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics |
| title_fullStr |
An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics |
| title_full_unstemmed |
An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics |
| title_sort |
atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/e8bbc178370d42f0a7884140d62b6b59 |
| work_keys_str_mv |
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