Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs

Cisplatin, a platinum chemotherapeutic agent, is widely used to treat several cancers. Here Yimit et al. revert to genome-wide approaches to map and analyze cisplatin damage formation and excision repair with single nucleotide resolution across different mice organs following platinum treatment.

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Autores principales: Askar Yimit, Ogun Adebali, Aziz Sancar, Yuchao Jiang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e8c9077bcabd4f6dbd5440dc994c0977
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