Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types

Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types

Abstract We hypothesized that an appropriate ratio of cardiomyocytes, fibroblasts, endothelial cells, and extracellular matrix (ECM) factors would be required for the development of three-dimensional cardiac tissues (3D-CTs) as drug screening systems. To verify this hypothesis, ECM-coated human-indu...

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Autores principales: Maki Takeda, Shigeru Miyagawa, Emiko Ito, Akima Harada, Noriko Mochizuki-Oda, Michiya Matsusaki, Mitsuru Akashi, Yoshiki Sawa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/e8d088719a1542128974b40335af742f
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