Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types
Abstract We hypothesized that an appropriate ratio of cardiomyocytes, fibroblasts, endothelial cells, and extracellular matrix (ECM) factors would be required for the development of three-dimensional cardiac tissues (3D-CTs) as drug screening systems. To verify this hypothesis, ECM-coated human-indu...
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Main Authors: | Maki Takeda, Shigeru Miyagawa, Emiko Ito, Akima Harada, Noriko Mochizuki-Oda, Michiya Matsusaki, Mitsuru Akashi, Yoshiki Sawa |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/e8d088719a1542128974b40335af742f |
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