Optimising cell aggregate expansion in a perfused hollow fibre bioreactor via mathematical modelling.

The need for efficient and controlled expansion of cell populations is paramount in tissue engineering. Hollow fibre bioreactors (HFBs) have the potential to meet this need, but only with improved understanding of how operating conditions and cell seeding strategy affect cell proliferation in the bi...

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Autores principales: Lloyd A C Chapman, Rebecca J Shipley, Jonathan P Whiteley, Marianne J Ellis, Helen M Byrne, Sarah L Waters
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/e8d7f704587d42848b1366cb2516c3ab
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