Effects of poor sleep on the immune cell landscape as assessed by single-cell analysis

Liu et al. use mass cytometry and single-cell RNA sequencing of healthy human blood samples to obtain a comprehensive human immune cell landscape when sleep duration is reduced. Their findings could provide highdimensional insight into the cellular and molecular mechanisms of pathologic conditions a...

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Autores principales: Xiuxing Liu, Binyao Chen, Zhaohao Huang, Runping Duan, He Li, Lihui Xie, Rong Wang, Zhaohuai Li, Yuehan Gao, Yingfeng Zheng, Wenru Su
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e8dc70b7415c4a6babbdda9affd52feb
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Sumario:Liu et al. use mass cytometry and single-cell RNA sequencing of healthy human blood samples to obtain a comprehensive human immune cell landscape when sleep duration is reduced. Their findings could provide highdimensional insight into the cellular and molecular mechanisms of pathologic conditions affect by poor sleep.