Leukocyte‐Derived High‐Mobility Group Box 1 Governs Hepatic Immune Responses to Listeria monocytogenes

Leukocyte‐Derived High‐Mobility Group Box 1 Governs Hepatic Immune Responses to Listeria monocytogenes

High‐mobility group box 1 (HMGB1) is a nucleoprotein with proinflammatory functions following cellular release during tissue damage. Moreover, antibody‐mediated HMGB1 neutralization alleviates lipopolysaccharide (LPS)‐induced shock, suggesting a role for HMGB1 as a superordinate therapeutic target f...

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Autores principales: Annika Volmari, Katharina Foelsch, Elisabeth Zierz, Karsten Yan, Minyue Qi, Karlotta Bartels, Stephanie Kondratowicz, Marius Boettcher, Daniel Reimers, Masahiro Nishibori, Keyue Liu, Robert F. Schwabe, Ansgar W. Lohse, Samuel Huber, Hans‐Willi Mittruecker, Peter Huebener
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
Materias:
Diseases of the digestive system. Gastroenterology
RC799-869
Acceso en línea:https://doaj.org/article/e8ddfffaf1494235a97e00fc6451d930
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