Regressing basal-cell carcinoma masquerading as benign lichenoid keratosis

Background: Benign lichenoid keratosis (BLK, LPLK) is often misdiagnosed clinically as superficial basal-cell carcinoma (BCC), especially when occurring on the trunk. However, BCCs undergoing regression may be associated with a lichenoid interface dermatitis that may be misinterpreted as BLK in his...

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Autores principales:	Aleksandra Kulberg, Wolfgang Weyers
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2016
Materias:	Basal-cell carcinoma benign lichenoid keratosis lichen planus-like keratosis. Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/e8e4c7ceae5b4b5b87f6619554bd6263
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spelling	oai:doaj.org-article:e8e4c7ceae5b4b5b87f6619554bd62632021-11-17T08:31:02ZRegressing basal-cell carcinoma masquerading as benign lichenoid keratosis10.5826/dpc.0604a032160-9381https://doaj.org/article/e8e4c7ceae5b4b5b87f6619554bd62632016-10-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/158https://doaj.org/toc/2160-9381 Background: Benign lichenoid keratosis (BLK, LPLK) is often misdiagnosed clinically as superficial basal-cell carcinoma (BCC), especially when occurring on the trunk. However, BCCs undergoing regression may be associated with a lichenoid interface dermatitis that may be misinterpreted as BLK in histopathologic sections. Methods: In order to assess the frequency of remnants of BCC in lesions interpreted as BLK, we performed step sections on 100 lesions from the trunk of male patients that had been diagnosed as BLK. Results: Deeper sections revealed remnants of superficial BCC in five and remnants of a melanocytic nevus in two specimens. In the original sections of cases in which a BCC showed up, crusts tended to be more common, whereas vacuolar changes at the dermo-epidermal junction and melanophages in the papillary dermis tended to be less common and less pronounced. Conclusions: Lesions from the trunk submitted as BCC and presenting histopathologically as a lichenoid interface dermatitis are not always BLKs. Although no confident recommendations can be given on the basis of this limited study, deeper sections may be warranted if lesions are crusted and/or associated with only minimal vacuolar changes at the dermo-epidermal junction and no or few melanophages in the papillary dermis. Aleksandra KulbergWolfgang WeyersMattioli1885articleBasal-cell carcinomabenign lichenoid keratosislichen planus-like keratosis.DermatologyRL1-803ENDermatology Practical & Conceptual (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Basal-cell carcinoma benign lichenoid keratosis lichen planus-like keratosis. Dermatology RL1-803
spellingShingle	Basal-cell carcinoma benign lichenoid keratosis lichen planus-like keratosis. Dermatology RL1-803 Aleksandra Kulberg Wolfgang Weyers Regressing basal-cell carcinoma masquerading as benign lichenoid keratosis
description	Background: Benign lichenoid keratosis (BLK, LPLK) is often misdiagnosed clinically as superficial basal-cell carcinoma (BCC), especially when occurring on the trunk. However, BCCs undergoing regression may be associated with a lichenoid interface dermatitis that may be misinterpreted as BLK in histopathologic sections. Methods: In order to assess the frequency of remnants of BCC in lesions interpreted as BLK, we performed step sections on 100 lesions from the trunk of male patients that had been diagnosed as BLK. Results: Deeper sections revealed remnants of superficial BCC in five and remnants of a melanocytic nevus in two specimens. In the original sections of cases in which a BCC showed up, crusts tended to be more common, whereas vacuolar changes at the dermo-epidermal junction and melanophages in the papillary dermis tended to be less common and less pronounced. Conclusions: Lesions from the trunk submitted as BCC and presenting histopathologically as a lichenoid interface dermatitis are not always BLKs. Although no confident recommendations can be given on the basis of this limited study, deeper sections may be warranted if lesions are crusted and/or associated with only minimal vacuolar changes at the dermo-epidermal junction and no or few melanophages in the papillary dermis.
format	article
author	Aleksandra Kulberg Wolfgang Weyers
author_facet	Aleksandra Kulberg Wolfgang Weyers
author_sort	Aleksandra Kulberg
title	Regressing basal-cell carcinoma masquerading as benign lichenoid keratosis
title_short	Regressing basal-cell carcinoma masquerading as benign lichenoid keratosis
title_full	Regressing basal-cell carcinoma masquerading as benign lichenoid keratosis
title_fullStr	Regressing basal-cell carcinoma masquerading as benign lichenoid keratosis
title_full_unstemmed	Regressing basal-cell carcinoma masquerading as benign lichenoid keratosis
title_sort	regressing basal-cell carcinoma masquerading as benign lichenoid keratosis
publisher	Mattioli1885
publishDate	2016
url	https://doaj.org/article/e8e4c7ceae5b4b5b87f6619554bd6263
work_keys_str_mv	AT aleksandrakulberg regressingbasalcellcarcinomamasqueradingasbenignlichenoidkeratosis AT wolfgangweyers regressingbasalcellcarcinomamasqueradingasbenignlichenoidkeratosis
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Regressing basal-cell carcinoma masquerading as benign lichenoid keratosis

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