Hepatic HuR modulates lipid homeostasis in response to high-fat diet

Human antigen R (HuR) is a RNA binding protein involved in the regulation of many cellular functions. Here the authors show that, hepatocyte specific deletion of HuR exacerbates high-fat diet-induced NAFLD in mice by regulating transcripts involved in lipid transport and ATP synthesis.

Guardado en:

Detalles Bibliográficos
Autores principales:	Zhuojun Zhang, Chen Zong, Mingyang Jiang, Han Hu, Xiaolei Cheng, Juhua Ni, Xia Yi, Bin Jiang, Feng Tian, Ming-Wen Chang, Wen Su, Lijun Zhu, Jinfan Li, Xueping Xiang, Congxiu Miao, Myriam Gorospe, Rafael de Cabo, Yali Dou, Zhenyu Ju, Jichun Yang, Changtao Jiang, Zhongzhou Yang, Wengong Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e8e60e544729458cb35c8c4647274ad2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Sea el primero en dejar un comentario!

Hepatic HuR modulates lipid homeostasis in response to high-fat diet

Ejemplares similares