Antiretroviral therapy use in selected countries in Latin America during 2013–2017: results from the Latin American Workshop in HIV Study Group

ABSTRACT: Objective: To document antiretroviral use in Latin America during the last decade. Methods: We collected indicators from 79 HIV health care centres in 14 Latin American Spanish-speaking countries for 2013–2017. Indicators were analysed by age, sex and other characteristics and weighted by...

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Autores principales: Pedro Zitko, Martin Hojman, Sofía Sabato, Pablo Parenti, Rosana Cuini, Liliana Calanni, Jorge Contarelli, Rosa Teran, Valeria Araujo, Ioannis Bakolis, Jorge Chaverri, Miguel Morales, Ana-Belen Arauz, Wendy Moncada, Mónica Thormann, Carlos Beltrán
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Publicado: Elsevier 2021
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spelling oai:doaj.org-article:e8ea1fd4e9f949e5b26c4942d44673c52021-11-14T04:31:14ZAntiretroviral therapy use in selected countries in Latin America during 2013–2017: results from the Latin American Workshop in HIV Study Group1201-971210.1016/j.ijid.2021.09.047https://doaj.org/article/e8ea1fd4e9f949e5b26c4942d44673c52021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1201971221007554https://doaj.org/toc/1201-9712ABSTRACT: Objective: To document antiretroviral use in Latin America during the last decade. Methods: We collected indicators from 79 HIV health care centres in 14 Latin American Spanish-speaking countries for 2013–2017. Indicators were analysed by age, sex and other characteristics and weighted by the estimated people under care (PUC) population in each country. Results: We gathered information on 116 299 PUC. One-third belonged to centres reporting a shortage of at least one antiretroviral therapy (ART) drug for >30 days during 2017. At end 2017, 95.1% of PUC were receiving ART. During 2013–2017, 45 329 people living with HIV were admitted to 39 centres. ART initiated during the first year after admission increased from 76.7% in 2013 to 83.8% in 2017. In 35 centres across the study period, 71.7% of PUC started ART with tenofovir disoproxil fumarate and lamivudine, and zidovudine use decreased. The third most common ART drug, EFV, reached 64.8%. Raltegravir and other alternatives increased annually to almost 10% of total use in 2017. Conclusions: Initial ART in Latin America is not based on the most recent scientific evidence and recommendations; use of drugs with higher efficacy and safety profiles and guarantee of ART availability continues to be a public health challenge.Pedro ZitkoMartin HojmanSofía SabatoPablo ParentiRosana CuiniLiliana CalanniJorge ContarelliRosa TeranValeria AraujoIoannis BakolisJorge ChaverriMiguel MoralesAna-Belen ArauzWendy MoncadaMónica ThormannCarlos BeltránElsevierarticleInfectious and parasitic diseasesRC109-216ENInternational Journal of Infectious Diseases, Vol 113, Iss , Pp 288-296 (2021)
institution DOAJ
collection DOAJ
language EN
topic Infectious and parasitic diseases
RC109-216
spellingShingle Infectious and parasitic diseases
RC109-216
Pedro Zitko
Martin Hojman
Sofía Sabato
Pablo Parenti
Rosana Cuini
Liliana Calanni
Jorge Contarelli
Rosa Teran
Valeria Araujo
Ioannis Bakolis
Jorge Chaverri
Miguel Morales
Ana-Belen Arauz
Wendy Moncada
Mónica Thormann
Carlos Beltrán
Antiretroviral therapy use in selected countries in Latin America during 2013–2017: results from the Latin American Workshop in HIV Study Group
description ABSTRACT: Objective: To document antiretroviral use in Latin America during the last decade. Methods: We collected indicators from 79 HIV health care centres in 14 Latin American Spanish-speaking countries for 2013–2017. Indicators were analysed by age, sex and other characteristics and weighted by the estimated people under care (PUC) population in each country. Results: We gathered information on 116 299 PUC. One-third belonged to centres reporting a shortage of at least one antiretroviral therapy (ART) drug for >30 days during 2017. At end 2017, 95.1% of PUC were receiving ART. During 2013–2017, 45 329 people living with HIV were admitted to 39 centres. ART initiated during the first year after admission increased from 76.7% in 2013 to 83.8% in 2017. In 35 centres across the study period, 71.7% of PUC started ART with tenofovir disoproxil fumarate and lamivudine, and zidovudine use decreased. The third most common ART drug, EFV, reached 64.8%. Raltegravir and other alternatives increased annually to almost 10% of total use in 2017. Conclusions: Initial ART in Latin America is not based on the most recent scientific evidence and recommendations; use of drugs with higher efficacy and safety profiles and guarantee of ART availability continues to be a public health challenge.
format article
author Pedro Zitko
Martin Hojman
Sofía Sabato
Pablo Parenti
Rosana Cuini
Liliana Calanni
Jorge Contarelli
Rosa Teran
Valeria Araujo
Ioannis Bakolis
Jorge Chaverri
Miguel Morales
Ana-Belen Arauz
Wendy Moncada
Mónica Thormann
Carlos Beltrán
author_facet Pedro Zitko
Martin Hojman
Sofía Sabato
Pablo Parenti
Rosana Cuini
Liliana Calanni
Jorge Contarelli
Rosa Teran
Valeria Araujo
Ioannis Bakolis
Jorge Chaverri
Miguel Morales
Ana-Belen Arauz
Wendy Moncada
Mónica Thormann
Carlos Beltrán
author_sort Pedro Zitko
title Antiretroviral therapy use in selected countries in Latin America during 2013–2017: results from the Latin American Workshop in HIV Study Group
title_short Antiretroviral therapy use in selected countries in Latin America during 2013–2017: results from the Latin American Workshop in HIV Study Group
title_full Antiretroviral therapy use in selected countries in Latin America during 2013–2017: results from the Latin American Workshop in HIV Study Group
title_fullStr Antiretroviral therapy use in selected countries in Latin America during 2013–2017: results from the Latin American Workshop in HIV Study Group
title_full_unstemmed Antiretroviral therapy use in selected countries in Latin America during 2013–2017: results from the Latin American Workshop in HIV Study Group
title_sort antiretroviral therapy use in selected countries in latin america during 2013–2017: results from the latin american workshop in hiv study group
publisher Elsevier
publishDate 2021
url https://doaj.org/article/e8ea1fd4e9f949e5b26c4942d44673c5
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