Analysis of Individuals from a Dengue-Endemic Region Helps Define the Footprint and Repertoire of Antibodies Targeting Dengue Virus 3 Type-Specific Epitopes

Analysis of Individuals from a Dengue-Endemic Region Helps Define the Footprint and Repertoire of Antibodies Targeting Dengue Virus 3 Type-Specific Epitopes

ABSTRACT The four dengue virus serotypes (DENV1 to 4) cause dengue, a major public health problem worldwide. Individuals exposed to primary DENV infections develop serotype-specific neutralizing antibodies, including strongly neutralizing antibodies targeting quaternary epitopes. To date, no studies...

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Bibliographic Details
Main Authors: Daniela V. Andrade, Leah C. Katzelnick, Doug G. Widman, Angel Balmaseda, Aravinda M. de Silva, Ralph S. Baric, Eva Harris
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
dengue virus
natural infection
neutralizing antibodies
quaternary epitope
repertoire
serotype-specific
Microbiology
QR1-502
Online Access:https://doaj.org/article/e8f9930e75c34557b9f210418582451d
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https://doaj.org/article/e8f9930e75c34557b9f210418582451d

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