Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity.
Gastrointestinal nematode parasites infect over 1 billion humans, with little evidence for generation of sterilising immunity. These helminths are highly adapted to their mammalian host, following a developmental program through successive niches, while effectively down-modulating host immune respon...
Guardado en:
Autores principales: | James P Hewitson, Al C Ivens, Yvonne Harcus, Kara J Filbey, Henry J McSorley, Janice Murray, Stephen Bridgett, David Ashford, Adam A Dowle, Rick M Maizels |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/e90175e6e0a34370b2d69d1430927d27 |
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