Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding
During cell division animal cells generate intracellular pressure and round against their environment, but the genes responsible for this are largely unknown. Here the authors use a microcantilever- and RNAi-based assay to screen > 1000 genes and identify 49 genes involved in mitotic cell roundin...
Guardado en:
Autores principales: | Yusuke Toyoda, Cedric J. Cattin, Martin P. Stewart, Ina Poser, Mirko Theis, Teymuras V. Kurzchalia, Frank Buchholz, Anthony A. Hyman, Daniel J. Müller |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e90be210e50b44a588340bc826ea3fc6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Memory of cell shape biases stochastic fate decision-making despite mitotic rounding
por: Takashi Akanuma, et al.
Publicado: (2016) -
Membrane invaginations reveal cortical sites that pull on mitotic spindles in one-cell C. elegans embryos.
por: Stefanie Redemann, et al.
Publicado: (2010) -
Mitotic chromosome binding predicts transcription factor properties in interphase
por: Mahé Raccaud, et al.
Publicado: (2019) -
Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans
por: Veronica Diez, et al.
Publicado: (2021) -
Molecular strategies of the Caenorhabditis elegans dauer larva to survive extreme desiccation.
por: Cihan Erkut, et al.
Publicado: (2013)