Nanoencapsulated rituximab mediates superior cellular immunity against metastatic B-cell lymphoma in a complement competent humanized mouse model

Background Despite the numerous applications of monoclonal antibodies (mAbs) in cancer therapeutics, animal models available to test the therapeutic efficacy of new mAbs are limited. NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice are one of the most highly immunodeficient strains and are universally us...

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Autores principales: Lan Wang, Jing Wen, Jie Ren, Emiko Kranz, Shilin Chen, Toshio Kanazawa, Irvin Chen, Yunfeng Lu, Masakazu Kamata
Formato: article
Lenguaje:EN
Publicado: BMJ Publishing Group 2021
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Acceso en línea:https://doaj.org/article/e913defc66ea41f4a4af89a8552834da
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