Mycobacterial MazG safeguards genetic stability via housecleaning of 5-OH-dCTP.
Generation of reactive oxygen species and reactive nitrogen species in phagocytes is an important innate immune response mechanism to eliminate microbial pathogens. It is known that deoxynucleotides (dNTPs), the precursor nucleotides to DNA synthesis, are one group of the significant targets for the...
Guardado en:
Autores principales: | Liang-Dong Lyu, Bi-Kui Tang, Xiao-Yong Fan, Hui Ma, Guo-Ping Zhao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/e9175808bc0549d0bee139b2c16ef4c8 |
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