The Association Between Lysosomal Storage Disorder Genes and Parkinson’s Disease: A Large Cohort Study in Chinese Mainland Population
Background: Recent years have witnessed an increasing number of studies indicating an essential role of the lysosomal dysfunction in Parkinson’s disease (PD) at the genetic, biochemical, and cellular pathway levels. In this study, we investigated the association between rare variants in lysosomal st...
Guardado en:
Autores principales: | Yu-wen Zhao, Hong-xu Pan, Zhenhua Liu, Yige Wang, Qian Zeng, Zheng-huan Fang, Teng-fei Luo, Kun Xu, Zheng Wang, Xun Zhou, Runcheng He, Bin Li, Guihu Zhao, Qian Xu, Qi-ying Sun, Xin-xiang Yan, Jie-qiong Tan, Jin-chen Li, Ji-feng Guo, Bei-sha Tang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e91aa4c6c749496789aa5c4675283a09 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Natural Products Induce Lysosomal Membrane Permeabilization as an Anticancer Strategy
por: Reginald Halaby
Publicado: (2021) -
Novel Approaches of Dysregulating Lysosome Functions in Cancer Cells by Specific Drugs and Its Nanoformulations: A Smart Approach of Modern Therapeutics
por: Allemailem KS, et al.
Publicado: (2021) -
TFEB Dependent Autophagy-Lysosomal Pathway: An Emerging Pharmacological Target in Sepsis
por: Xin Liu, et al.
Publicado: (2021) -
Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells
por: Sabrina Sofia Burgener, et al.
Publicado: (2021) -
Nano-hydroxyapatite accelerates vascular calcification via lysosome impairment and autophagy dysfunction in smooth muscle cells
por: Qi Liu, et al.
Publicado: (2022)