Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking

Regeneration of skeletal muscle is accompanied by a transitory inflammatory phase. Here the authors show that the complement C3 component is activated following muscle injury, and signals through the alternative complement pathway to regulate immune cell infiltration and muscle regeneration.

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Autores principales:	Congcong Zhang, Chunxiao Wang, Yulin Li, Takashi Miwa, Chang Liu, Wei Cui, Wen-Chao Song, Jie Du
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e91c93ba282f4a14988e85085d444162
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spelling	oai:doaj.org-article:e91c93ba282f4a14988e85085d4441622021-12-02T17:06:00ZComplement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking10.1038/s41467-017-01526-z2041-1723https://doaj.org/article/e91c93ba282f4a14988e85085d4441622017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01526-zhttps://doaj.org/toc/2041-1723Regeneration of skeletal muscle is accompanied by a transitory inflammatory phase. Here the authors show that the complement C3 component is activated following muscle injury, and signals through the alternative complement pathway to regulate immune cell infiltration and muscle regeneration.Congcong ZhangChunxiao WangYulin LiTakashi MiwaChang LiuWei CuiWen-Chao SongJie DuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Congcong Zhang Chunxiao Wang Yulin Li Takashi Miwa Chang Liu Wei Cui Wen-Chao Song Jie Du Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking
description	Regeneration of skeletal muscle is accompanied by a transitory inflammatory phase. Here the authors show that the complement C3 component is activated following muscle injury, and signals through the alternative complement pathway to regulate immune cell infiltration and muscle regeneration.
format	article
author	Congcong Zhang Chunxiao Wang Yulin Li Takashi Miwa Chang Liu Wei Cui Wen-Chao Song Jie Du
author_facet	Congcong Zhang Chunxiao Wang Yulin Li Takashi Miwa Chang Liu Wei Cui Wen-Chao Song Jie Du
author_sort	Congcong Zhang
title	Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking
title_short	Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking
title_full	Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking
title_fullStr	Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking
title_full_unstemmed	Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking
title_sort	complement c3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e91c93ba282f4a14988e85085d444162
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_version_	1718381765176852480

Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking

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