MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors

Mesodermal iPSC-derived progenitors (MiPs) can regenerate both skeletal and cardiac muscle. Here, the authors show that a microRNA cocktail stimulates skeletal muscle differentiation and that human MiPs can engraft into striated muscle in mice.

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Autores principales:	Giorgia Giacomazzi, Bryan Holvoet, Sander Trenson, Ellen Caluwé, Bojana Kravic, Hanne Grosemans, Álvaro Cortés-Calabuig, Christophe M. Deroose, Danny Huylebroeck, Said Hashemolhosseini, Stefan Janssens, Elizabeth McNally, Mattia Quattrocelli, Maurilio Sampaolesi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e92068e1fa5d401cb076a3ec19008468
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spelling	oai:doaj.org-article:e92068e1fa5d401cb076a3ec190084682021-12-02T14:42:03ZMicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors10.1038/s41467-017-01359-w2041-1723https://doaj.org/article/e92068e1fa5d401cb076a3ec190084682017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01359-whttps://doaj.org/toc/2041-1723Mesodermal iPSC-derived progenitors (MiPs) can regenerate both skeletal and cardiac muscle. Here, the authors show that a microRNA cocktail stimulates skeletal muscle differentiation and that human MiPs can engraft into striated muscle in mice.Giorgia GiacomazziBryan HolvoetSander TrensonEllen CaluwéBojana KravicHanne GrosemansÁlvaro Cortés-CalabuigChristophe M. DerooseDanny HuylebroeckSaid HashemolhosseiniStefan JanssensElizabeth McNallyMattia QuattrocelliMaurilio SampaolesiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Giorgia Giacomazzi Bryan Holvoet Sander Trenson Ellen Caluwé Bojana Kravic Hanne Grosemans Álvaro Cortés-Calabuig Christophe M. Deroose Danny Huylebroeck Said Hashemolhosseini Stefan Janssens Elizabeth McNally Mattia Quattrocelli Maurilio Sampaolesi MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors
description	Mesodermal iPSC-derived progenitors (MiPs) can regenerate both skeletal and cardiac muscle. Here, the authors show that a microRNA cocktail stimulates skeletal muscle differentiation and that human MiPs can engraft into striated muscle in mice.
format	article
author	Giorgia Giacomazzi Bryan Holvoet Sander Trenson Ellen Caluwé Bojana Kravic Hanne Grosemans Álvaro Cortés-Calabuig Christophe M. Deroose Danny Huylebroeck Said Hashemolhosseini Stefan Janssens Elizabeth McNally Mattia Quattrocelli Maurilio Sampaolesi
author_facet	Giorgia Giacomazzi Bryan Holvoet Sander Trenson Ellen Caluwé Bojana Kravic Hanne Grosemans Álvaro Cortés-Calabuig Christophe M. Deroose Danny Huylebroeck Said Hashemolhosseini Stefan Janssens Elizabeth McNally Mattia Quattrocelli Maurilio Sampaolesi
author_sort	Giorgia Giacomazzi
title	MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors
title_short	MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors
title_full	MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors
title_fullStr	MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors
title_full_unstemmed	MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors
title_sort	micrornas promote skeletal muscle differentiation of mesodermal ipsc-derived progenitors
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e92068e1fa5d401cb076a3ec19008468
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MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors

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