Long-term corticosteroid-induced chronic glaucoma model produced by intracameral injection of dexamethasone-loaded PLGA microspheres

Long-term corticosteroid-induced chronic glaucoma model produced by intracameral injection of dexamethasone-loaded PLGA microspheres

Purpose To evaluate a new chronic glaucoma model produced by intracameral injection of dexamethasone-loaded poly lactic-co-glycolic acid microspheres (Dex-PLGA-Ms) over six months. Methods Healthy rats received two injections (at baseline and Week 4) of Dex-PLGA-Ms into the anterior chamber of the r...

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Detalles Bibliográficos
Autores principales: MJ Rodrigo, D Garcia-Herranz, A Aragón-Navas, M Subias, T Martinez-Rincón, S Mendez-Martínez, MJ Cardiel, J García-Feijoo, J Ruberte, R Herrero-Vanrell, L Pablo, E Garcia-Martin, I Bravo-Osuna
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2021
Materias:
glaucoma
animal model
plga microspheres
neurodegeneration
dexamethasone
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/e922018f63d543ec9289e68fb4866160
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