Overexpressing STAMP2 improves insulin resistance in diabetic ApoE⁻/⁻/LDLR⁻/⁻ mice via macrophage polarization shift in adipose tissues.

STAMP2 is a counterregulator of inflammation and insulin resistance. The aim of this study is to investigate whether activation of STAMP2 improves insulin resistance by regulating macrophage polarization in adipose tissues. The diabetic ApoE⁻/⁻/LDLR⁻/⁻ mouse model was induced by high-fat diet and lo...

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Auteurs principaux: Lu Han, Meng-Xiong Tang, Yun Ti, Zhi-Hao Wang, Jia Wang, Wen-Yuan Ding, Hua Wang, Yun Zhang, Wei Zhang, Ming Zhong
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/e92c32cc8b4648a0b88f28b3eb2e4887
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