Universality of thermodynamic constants governing biological growth rates.

<h4>Background</h4>Mathematical models exist that quantify the effect of temperature on poikilotherm growth rate. One family of such models assumes a single rate-limiting 'master reaction' using terms describing the temperature-dependent denaturation of the reaction's enzy...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ross Corkrey, June Olley, David Ratkowsky, Tom McMeekin, Tom Ross
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e92c4df119f24d438fce78bea3e714dd
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e92c4df119f24d438fce78bea3e714dd
record_format	dspace
spelling	oai:doaj.org-article:e92c4df119f24d438fce78bea3e714dd2021-11-18T07:28:18ZUniversality of thermodynamic constants governing biological growth rates.1932-620310.1371/journal.pone.0032003https://doaj.org/article/e92c4df119f24d438fce78bea3e714dd2012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22348140/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Mathematical models exist that quantify the effect of temperature on poikilotherm growth rate. One family of such models assumes a single rate-limiting 'master reaction' using terms describing the temperature-dependent denaturation of the reaction's enzyme. We consider whether such a model can describe growth in each domain of life.<h4>Methodology/principal findings</h4>A new model based on this assumption and using a hierarchical Bayesian approach fits simultaneously 95 data sets for temperature-related growth rates of diverse microorganisms from all three domains of life, Bacteria, Archaea and Eukarya. Remarkably, the model produces credible estimates of fundamental thermodynamic parameters describing protein thermal stability predicted over 20 years ago.<h4>Conclusions/significance</h4>The analysis lends support to the concept of universal thermodynamic limits to microbial growth rate dictated by protein thermal stability that in turn govern biological rates. This suggests that the thermal stability of proteins is a unifying property in the evolution and adaptation of life on earth. The fundamental nature of this conclusion has importance for many fields of study including microbiology, protein chemistry, thermal biology, and ecological theory including, for example, the influence of the vast microbial biomass and activity in the biosphere that is poorly described in current climate models.Ross CorkreyJune OlleyDavid RatkowskyTom McMeekinTom RossPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 2, p e32003 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ross Corkrey June Olley David Ratkowsky Tom McMeekin Tom Ross Universality of thermodynamic constants governing biological growth rates.
description	<h4>Background</h4>Mathematical models exist that quantify the effect of temperature on poikilotherm growth rate. One family of such models assumes a single rate-limiting 'master reaction' using terms describing the temperature-dependent denaturation of the reaction's enzyme. We consider whether such a model can describe growth in each domain of life.<h4>Methodology/principal findings</h4>A new model based on this assumption and using a hierarchical Bayesian approach fits simultaneously 95 data sets for temperature-related growth rates of diverse microorganisms from all three domains of life, Bacteria, Archaea and Eukarya. Remarkably, the model produces credible estimates of fundamental thermodynamic parameters describing protein thermal stability predicted over 20 years ago.<h4>Conclusions/significance</h4>The analysis lends support to the concept of universal thermodynamic limits to microbial growth rate dictated by protein thermal stability that in turn govern biological rates. This suggests that the thermal stability of proteins is a unifying property in the evolution and adaptation of life on earth. The fundamental nature of this conclusion has importance for many fields of study including microbiology, protein chemistry, thermal biology, and ecological theory including, for example, the influence of the vast microbial biomass and activity in the biosphere that is poorly described in current climate models.
format	article
author	Ross Corkrey June Olley David Ratkowsky Tom McMeekin Tom Ross
author_facet	Ross Corkrey June Olley David Ratkowsky Tom McMeekin Tom Ross
author_sort	Ross Corkrey
title	Universality of thermodynamic constants governing biological growth rates.
title_short	Universality of thermodynamic constants governing biological growth rates.
title_full	Universality of thermodynamic constants governing biological growth rates.
title_fullStr	Universality of thermodynamic constants governing biological growth rates.
title_full_unstemmed	Universality of thermodynamic constants governing biological growth rates.
title_sort	universality of thermodynamic constants governing biological growth rates.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/e92c4df119f24d438fce78bea3e714dd
work_keys_str_mv	AT rosscorkrey universalityofthermodynamicconstantsgoverningbiologicalgrowthrates AT juneolley universalityofthermodynamicconstantsgoverningbiologicalgrowthrates AT davidratkowsky universalityofthermodynamicconstantsgoverningbiologicalgrowthrates AT tommcmeekin universalityofthermodynamicconstantsgoverningbiologicalgrowthrates AT tomross universalityofthermodynamicconstantsgoverningbiologicalgrowthrates
_version_	1718423445602041856

Universality of thermodynamic constants governing biological growth rates.

Ejemplares similares