MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies

Oncogene addiction is considered as a cancer cell-autonomous phenomenon, but can also influence the host immune system. Here the authors show that MYC-driven lymphomagenesis is associated with a block in the maturation and effector functions of natural killer cells as a mechanism of tumor escape fro...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Srividya Swaminathan, Aida S. Hansen, Line D. Heftdal, Renumathy Dhanasekaran, Anja Deutzmann, Wadie D. M. Fernandez, Daniel F. Liefwalker, Crista Horton, Adriane Mosley, Mariola Liebersbach, Holden T. Maecker, Dean W. Felsher
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Q
Accès en ligne:https://doaj.org/article/e934ba6da0f2436b96b15ce1e0b4094b
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!