Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family

Cellular uptake of transition metal ions is mediated by members of the SLC11/NRAMP family. Here the authors determine the structural and functional properties of EcoDMT, a bacterial SLC11 transporter, gathering molecular insight into its transport mechanism and proton coupling process.

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Autores principales:	Ines A. Ehrnstorfer, Cristina Manatschal, Fabian M. Arnold, Juerg Laederach, Raimund Dutzler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e9441990259848e79900033d866018d5
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spelling	oai:doaj.org-article:e9441990259848e79900033d866018d52021-12-02T14:42:37ZStructural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family10.1038/ncomms140332041-1723https://doaj.org/article/e9441990259848e79900033d866018d52017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14033https://doaj.org/toc/2041-1723Cellular uptake of transition metal ions is mediated by members of the SLC11/NRAMP family. Here the authors determine the structural and functional properties of EcoDMT, a bacterial SLC11 transporter, gathering molecular insight into its transport mechanism and proton coupling process.Ines A. EhrnstorferCristina ManatschalFabian M. ArnoldJuerg LaederachRaimund DutzlerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ines A. Ehrnstorfer Cristina Manatschal Fabian M. Arnold Juerg Laederach Raimund Dutzler Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
description	Cellular uptake of transition metal ions is mediated by members of the SLC11/NRAMP family. Here the authors determine the structural and functional properties of EcoDMT, a bacterial SLC11 transporter, gathering molecular insight into its transport mechanism and proton coupling process.
format	article
author	Ines A. Ehrnstorfer Cristina Manatschal Fabian M. Arnold Juerg Laederach Raimund Dutzler
author_facet	Ines A. Ehrnstorfer Cristina Manatschal Fabian M. Arnold Juerg Laederach Raimund Dutzler
author_sort	Ines A. Ehrnstorfer
title	Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
title_short	Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
title_full	Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
title_fullStr	Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
title_full_unstemmed	Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
title_sort	structural and mechanistic basis of proton-coupled metal ion transport in the slc11/nramp family
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e9441990259848e79900033d866018d5
work_keys_str_mv	AT inesaehrnstorfer structuralandmechanisticbasisofprotoncoupledmetaliontransportintheslc11nrampfamily AT cristinamanatschal structuralandmechanisticbasisofprotoncoupledmetaliontransportintheslc11nrampfamily AT fabianmarnold structuralandmechanisticbasisofprotoncoupledmetaliontransportintheslc11nrampfamily AT juerglaederach structuralandmechanisticbasisofprotoncoupledmetaliontransportintheslc11nrampfamily AT raimunddutzler structuralandmechanisticbasisofprotoncoupledmetaliontransportintheslc11nrampfamily
_version_	1718389664748929024

Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family

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