Bayesian Estimations of Exponential Distribution Based on Interval-Censored Data with a Cure Fraction

Censored data are considered to be of the interval type where the upper and lower bounds of an event’s failure time cannot be directly observed but only determined between interval inspection times. The analyses of interval-censored data have attracted attention because they are common in the fields...

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Autor principal: Al Omari Mohammed Ahmed
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Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/e94ba44ac70d4e11b9f3467159a0a347
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spelling oai:doaj.org-article:e94ba44ac70d4e11b9f3467159a0a3472021-11-08T02:36:23ZBayesian Estimations of Exponential Distribution Based on Interval-Censored Data with a Cure Fraction2314-478510.1155/2021/9822870https://doaj.org/article/e94ba44ac70d4e11b9f3467159a0a3472021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/9822870https://doaj.org/toc/2314-4785Censored data are considered to be of the interval type where the upper and lower bounds of an event’s failure time cannot be directly observed but only determined between interval inspection times. The analyses of interval-censored data have attracted attention because they are common in the fields of reliability and medicine. A proportion of patients enrolled in clinical trials can sometimes be cured. In some instances, their symptoms mostly disappear without any recurrence of the disease. In this study, the proportion of such patients who are cured is estimated. Furthermore, the Bayesian approach under the gamma prior and maximum likelihood estimation (MLE) is used to estimate the cure fraction depending on the bounded cumulative hazard (BCH) model based on interval-censored data with an exponential distribution. The Bayesian approach uses three loss functions: squared error, linear exponential, and general entropy. These functions are compared with the MLE and used between estimators. Moreover, they are obtained using the mean squared error, which locates the best option to estimate the parameter of an exponential distribution. The results show that the BCH model and lambda parameter of the exponential distribution based on the interval-censored data can be best estimated using the Bayesian gamma prior with a positive loss function of the linear exponential.Al Omari Mohammed AhmedHindawi LimitedarticleMathematicsQA1-939ENJournal of Mathematics, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Mathematics
QA1-939
spellingShingle Mathematics
QA1-939
Al Omari Mohammed Ahmed
Bayesian Estimations of Exponential Distribution Based on Interval-Censored Data with a Cure Fraction
description Censored data are considered to be of the interval type where the upper and lower bounds of an event’s failure time cannot be directly observed but only determined between interval inspection times. The analyses of interval-censored data have attracted attention because they are common in the fields of reliability and medicine. A proportion of patients enrolled in clinical trials can sometimes be cured. In some instances, their symptoms mostly disappear without any recurrence of the disease. In this study, the proportion of such patients who are cured is estimated. Furthermore, the Bayesian approach under the gamma prior and maximum likelihood estimation (MLE) is used to estimate the cure fraction depending on the bounded cumulative hazard (BCH) model based on interval-censored data with an exponential distribution. The Bayesian approach uses three loss functions: squared error, linear exponential, and general entropy. These functions are compared with the MLE and used between estimators. Moreover, they are obtained using the mean squared error, which locates the best option to estimate the parameter of an exponential distribution. The results show that the BCH model and lambda parameter of the exponential distribution based on the interval-censored data can be best estimated using the Bayesian gamma prior with a positive loss function of the linear exponential.
format article
author Al Omari Mohammed Ahmed
author_facet Al Omari Mohammed Ahmed
author_sort Al Omari Mohammed Ahmed
title Bayesian Estimations of Exponential Distribution Based on Interval-Censored Data with a Cure Fraction
title_short Bayesian Estimations of Exponential Distribution Based on Interval-Censored Data with a Cure Fraction
title_full Bayesian Estimations of Exponential Distribution Based on Interval-Censored Data with a Cure Fraction
title_fullStr Bayesian Estimations of Exponential Distribution Based on Interval-Censored Data with a Cure Fraction
title_full_unstemmed Bayesian Estimations of Exponential Distribution Based on Interval-Censored Data with a Cure Fraction
title_sort bayesian estimations of exponential distribution based on interval-censored data with a cure fraction
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/e94ba44ac70d4e11b9f3467159a0a347
work_keys_str_mv AT alomarimohammedahmed bayesianestimationsofexponentialdistributionbasedonintervalcensoreddatawithacurefraction
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