Efficacy of autologous platelets in macular hole surgery

Aristeidis Konstantinidis,1,2 Mark Hero,2 Panagiotis Nanos,1 Georgios D Panos1,3 1Department of Ophthalmology, University Hospital of Alexandroupolis, Alexandroupolis, Greece; 2Opthalmology Department, University Hospital Coventry and Warwickshire, Coventry, UK; 3Department of Ophthalmology, Univers...

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Autores principales: Konstantinidis A, Hero M, Nanos P, Panos GD
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Lenguaje:EN
Publicado: Dove Medical Press 2013
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Acceso en línea:https://doaj.org/article/e9538b7d6e2247bc9fcbf4b284c1da52
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spelling oai:doaj.org-article:e9538b7d6e2247bc9fcbf4b284c1da522021-12-02T02:42:15ZEfficacy of autologous platelets in macular hole surgery1177-54671177-5483https://doaj.org/article/e9538b7d6e2247bc9fcbf4b284c1da522013-04-01T00:00:00Zhttp://www.dovepress.com/efficacy-of-autologous-platelets-in-macular-hole-surgery-a12791https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Aristeidis Konstantinidis,1,2 Mark Hero,2 Panagiotis Nanos,1 Georgios D Panos1,3 1Department of Ophthalmology, University Hospital of Alexandroupolis, Alexandroupolis, Greece; 2Opthalmology Department, University Hospital Coventry and Warwickshire, Coventry, UK; 3Department of Ophthalmology, University Hospitals of Geneva, Geneva, Switzerland Abstract: The introduction of optical coherence tomography has allowed accurate measurement of the size of macular holes. A retrospective consecutive review was performed of 21 patients undergoing macular hole repair with vitrectomy, gas tamponade, and autologous platelet injection and we assessed the effect of macular hole parameters on anatomic and functional outcomes. We looked at the demographic features, final visual outcome, and anatomical closure. Twenty-one patients were included in the study. They underwent routine vitrectomy with gas tamponade (C3F8) and injection of autologous platelets. All patients were advised to maintain a facedown posture for 2 weeks. Anatomical closure was confirmed in all cases and 20 out of 21 of patients had improved postoperative visual acuity by two or more lines. In our series, the macular hole dimensions did not have much effect on the final results. The use of autologous platelets and strict facedown posture seems to be the deciding factor in good anatomical and visual outcome irrespective of macular hole dimensions. Keywords: macular hole, platelets, vitrectomyKonstantinidis AHero MNanos PPanos GDDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 745-750 (2013)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Konstantinidis A
Hero M
Nanos P
Panos GD
Efficacy of autologous platelets in macular hole surgery
description Aristeidis Konstantinidis,1,2 Mark Hero,2 Panagiotis Nanos,1 Georgios D Panos1,3 1Department of Ophthalmology, University Hospital of Alexandroupolis, Alexandroupolis, Greece; 2Opthalmology Department, University Hospital Coventry and Warwickshire, Coventry, UK; 3Department of Ophthalmology, University Hospitals of Geneva, Geneva, Switzerland Abstract: The introduction of optical coherence tomography has allowed accurate measurement of the size of macular holes. A retrospective consecutive review was performed of 21 patients undergoing macular hole repair with vitrectomy, gas tamponade, and autologous platelet injection and we assessed the effect of macular hole parameters on anatomic and functional outcomes. We looked at the demographic features, final visual outcome, and anatomical closure. Twenty-one patients were included in the study. They underwent routine vitrectomy with gas tamponade (C3F8) and injection of autologous platelets. All patients were advised to maintain a facedown posture for 2 weeks. Anatomical closure was confirmed in all cases and 20 out of 21 of patients had improved postoperative visual acuity by two or more lines. In our series, the macular hole dimensions did not have much effect on the final results. The use of autologous platelets and strict facedown posture seems to be the deciding factor in good anatomical and visual outcome irrespective of macular hole dimensions. Keywords: macular hole, platelets, vitrectomy
format article
author Konstantinidis A
Hero M
Nanos P
Panos GD
author_facet Konstantinidis A
Hero M
Nanos P
Panos GD
author_sort Konstantinidis A
title Efficacy of autologous platelets in macular hole surgery
title_short Efficacy of autologous platelets in macular hole surgery
title_full Efficacy of autologous platelets in macular hole surgery
title_fullStr Efficacy of autologous platelets in macular hole surgery
title_full_unstemmed Efficacy of autologous platelets in macular hole surgery
title_sort efficacy of autologous platelets in macular hole surgery
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/e9538b7d6e2247bc9fcbf4b284c1da52
work_keys_str_mv AT konstantinidisa efficacyofautologousplateletsinmacularholesurgery
AT herom efficacyofautologousplateletsinmacularholesurgery
AT nanosp efficacyofautologousplateletsinmacularholesurgery
AT panosgd efficacyofautologousplateletsinmacularholesurgery
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