Efficacy of autologous platelets in macular hole surgery
Aristeidis Konstantinidis,1,2 Mark Hero,2 Panagiotis Nanos,1 Georgios D Panos1,3 1Department of Ophthalmology, University Hospital of Alexandroupolis, Alexandroupolis, Greece; 2Opthalmology Department, University Hospital Coventry and Warwickshire, Coventry, UK; 3Department of Ophthalmology, Univers...
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Dove Medical Press
2013
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oai:doaj.org-article:e9538b7d6e2247bc9fcbf4b284c1da522021-12-02T02:42:15ZEfficacy of autologous platelets in macular hole surgery1177-54671177-5483https://doaj.org/article/e9538b7d6e2247bc9fcbf4b284c1da522013-04-01T00:00:00Zhttp://www.dovepress.com/efficacy-of-autologous-platelets-in-macular-hole-surgery-a12791https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Aristeidis Konstantinidis,1,2 Mark Hero,2 Panagiotis Nanos,1 Georgios D Panos1,3 1Department of Ophthalmology, University Hospital of Alexandroupolis, Alexandroupolis, Greece; 2Opthalmology Department, University Hospital Coventry and Warwickshire, Coventry, UK; 3Department of Ophthalmology, University Hospitals of Geneva, Geneva, Switzerland Abstract: The introduction of optical coherence tomography has allowed accurate measurement of the size of macular holes. A retrospective consecutive review was performed of 21 patients undergoing macular hole repair with vitrectomy, gas tamponade, and autologous platelet injection and we assessed the effect of macular hole parameters on anatomic and functional outcomes. We looked at the demographic features, final visual outcome, and anatomical closure. Twenty-one patients were included in the study. They underwent routine vitrectomy with gas tamponade (C3F8) and injection of autologous platelets. All patients were advised to maintain a facedown posture for 2 weeks. Anatomical closure was confirmed in all cases and 20 out of 21 of patients had improved postoperative visual acuity by two or more lines. In our series, the macular hole dimensions did not have much effect on the final results. The use of autologous platelets and strict facedown posture seems to be the deciding factor in good anatomical and visual outcome irrespective of macular hole dimensions. Keywords: macular hole, platelets, vitrectomyKonstantinidis AHero MNanos PPanos GDDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 745-750 (2013) |
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Ophthalmology RE1-994 Konstantinidis A Hero M Nanos P Panos GD Efficacy of autologous platelets in macular hole surgery |
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Aristeidis Konstantinidis,1,2 Mark Hero,2 Panagiotis Nanos,1 Georgios D Panos1,3 1Department of Ophthalmology, University Hospital of Alexandroupolis, Alexandroupolis, Greece; 2Opthalmology Department, University Hospital Coventry and Warwickshire, Coventry, UK; 3Department of Ophthalmology, University Hospitals of Geneva, Geneva, Switzerland Abstract: The introduction of optical coherence tomography has allowed accurate measurement of the size of macular holes. A retrospective consecutive review was performed of 21 patients undergoing macular hole repair with vitrectomy, gas tamponade, and autologous platelet injection and we assessed the effect of macular hole parameters on anatomic and functional outcomes. We looked at the demographic features, final visual outcome, and anatomical closure. Twenty-one patients were included in the study. They underwent routine vitrectomy with gas tamponade (C3F8) and injection of autologous platelets. All patients were advised to maintain a facedown posture for 2 weeks. Anatomical closure was confirmed in all cases and 20 out of 21 of patients had improved postoperative visual acuity by two or more lines. In our series, the macular hole dimensions did not have much effect on the final results. The use of autologous platelets and strict facedown posture seems to be the deciding factor in good anatomical and visual outcome irrespective of macular hole dimensions. Keywords: macular hole, platelets, vitrectomy |
format |
article |
author |
Konstantinidis A Hero M Nanos P Panos GD |
author_facet |
Konstantinidis A Hero M Nanos P Panos GD |
author_sort |
Konstantinidis A |
title |
Efficacy of autologous platelets in macular hole surgery |
title_short |
Efficacy of autologous platelets in macular hole surgery |
title_full |
Efficacy of autologous platelets in macular hole surgery |
title_fullStr |
Efficacy of autologous platelets in macular hole surgery |
title_full_unstemmed |
Efficacy of autologous platelets in macular hole surgery |
title_sort |
efficacy of autologous platelets in macular hole surgery |
publisher |
Dove Medical Press |
publishDate |
2013 |
url |
https://doaj.org/article/e9538b7d6e2247bc9fcbf4b284c1da52 |
work_keys_str_mv |
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1718402256926146560 |