Loss of FBP1 by aPKC-ι/Snail Pathway-Mediated Repression Promotes Invasion and Aerobic Glycolysis of Intrahepatic Cholangiocarcinoma

Intrahepatic cholangiocarcinoma (ICC) is one of the most commonly diagnosed malignancies worldwide, and the second most common primary liver tumor. The lack of effective diagnostic and treatment methods results in poor patient prognosis and high mortality rate. Atypical protein kinase C-ι (aPKC-ι) i...

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Bibliographic Details
Main Authors: Meng Gao, Chengjie Mei, Yonghua Guo, Peng Xia, Hao Zhang, Yinyi Liu, Ye Yao, Xiang Jiang, Yufeng Yuan, Yawei Qian
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
EMT
Online Access:https://doaj.org/article/e958f258e9914b1cbb0b1deffd831692
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