Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI
Acute kidney injury (AKI) is common after cardiac surgery. To date, there are no specific pharmacological therapies. In this review, we summarise the existing evidence for prevention and management of cardiac surgery-associated AKI and outline areas for future research. Preoperatively, angiotensin-c...
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MDPI AG
2021
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oai:doaj.org-article:e95cd90984504f1ea79016eac84aade02021-11-25T18:01:24ZCardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI10.3390/jcm102252852077-0383https://doaj.org/article/e95cd90984504f1ea79016eac84aade02021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/22/5285https://doaj.org/toc/2077-0383Acute kidney injury (AKI) is common after cardiac surgery. To date, there are no specific pharmacological therapies. In this review, we summarise the existing evidence for prevention and management of cardiac surgery-associated AKI and outline areas for future research. Preoperatively, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers should be withheld and nephrotoxins should be avoided to reduce the risk. Intraoperative strategies include goal-directed therapy with individualised blood pressure management and administration of balanced fluids, the use of circuits with biocompatible coatings, application of minimally invasive extracorporeal circulation, and lung protective ventilation. Postoperative management should be in accordance with current KDIGO AKI recommendations.Marlies OstermannGudrun KunstEleanor BakerKittisak WeerapolchaiNuttha LumlertgulMDPI AGarticleacute kidney injury (AKI)cardiac surgerycardiac surgery associated AKIpreventionmanagementcardiovascularMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5285, p 5285 (2021) |
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acute kidney injury (AKI) cardiac surgery cardiac surgery associated AKI prevention management cardiovascular Medicine R |
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acute kidney injury (AKI) cardiac surgery cardiac surgery associated AKI prevention management cardiovascular Medicine R Marlies Ostermann Gudrun Kunst Eleanor Baker Kittisak Weerapolchai Nuttha Lumlertgul Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI |
description |
Acute kidney injury (AKI) is common after cardiac surgery. To date, there are no specific pharmacological therapies. In this review, we summarise the existing evidence for prevention and management of cardiac surgery-associated AKI and outline areas for future research. Preoperatively, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers should be withheld and nephrotoxins should be avoided to reduce the risk. Intraoperative strategies include goal-directed therapy with individualised blood pressure management and administration of balanced fluids, the use of circuits with biocompatible coatings, application of minimally invasive extracorporeal circulation, and lung protective ventilation. Postoperative management should be in accordance with current KDIGO AKI recommendations. |
format |
article |
author |
Marlies Ostermann Gudrun Kunst Eleanor Baker Kittisak Weerapolchai Nuttha Lumlertgul |
author_facet |
Marlies Ostermann Gudrun Kunst Eleanor Baker Kittisak Weerapolchai Nuttha Lumlertgul |
author_sort |
Marlies Ostermann |
title |
Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI |
title_short |
Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI |
title_full |
Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI |
title_fullStr |
Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI |
title_full_unstemmed |
Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI |
title_sort |
cardiac surgery associated aki prevention strategies and medical treatment for csa-aki |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/e95cd90984504f1ea79016eac84aade0 |
work_keys_str_mv |
AT marliesostermann cardiacsurgeryassociatedakipreventionstrategiesandmedicaltreatmentforcsaaki AT gudrunkunst cardiacsurgeryassociatedakipreventionstrategiesandmedicaltreatmentforcsaaki AT eleanorbaker cardiacsurgeryassociatedakipreventionstrategiesandmedicaltreatmentforcsaaki AT kittisakweerapolchai cardiacsurgeryassociatedakipreventionstrategiesandmedicaltreatmentforcsaaki AT nutthalumlertgul cardiacsurgeryassociatedakipreventionstrategiesandmedicaltreatmentforcsaaki |
_version_ |
1718411776223084544 |