Application of the Fibrous Autograft in Posttraumatic Bone Regeneration of the Lower Jaw

The search for new types of bone substitutes is one of the topical problems of biology and medicine. The paper considered the role of fibrous autograft in reparative bone regeneration in the rat’s lower jaw model. Thirty Wistar rats were taken in the experiment: 15 in the experimental and 15 in the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Vladimir A. Usachev, Olga S. Artashyan, Vyacheslav V. Kotomtsev, Gleb S. Senkin, Daria A. Solosina
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/e95cec5c858b4199a0a8878c3dfdca40
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:e95cec5c858b4199a0a8878c3dfdca40
record_format dspace
spelling oai:doaj.org-article:e95cec5c858b4199a0a8878c3dfdca402021-11-23T06:14:42ZApplication of the Fibrous Autograft in Posttraumatic Bone Regeneration of the Lower Jaw2541-94202587-959610.29413/ABS.2019-4.1.25https://doaj.org/article/e95cec5c858b4199a0a8878c3dfdca402019-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1994https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The search for new types of bone substitutes is one of the topical problems of biology and medicine. The paper considered the role of fibrous autograft in reparative bone regeneration in the rat’s lower jaw model. Thirty Wistar rats were taken in the experiment: 15 in the experimental and 15 in the control group. Fibrous autograft was formed on the cellophane basis under the skin on the back of rats. Injury in the lower jaw with a diameter of 2 mm was formed and a fibrous graft was placed in injuries in the experimental group. Five animals from each groups were sacrificed at the first, third and fifth weeks of the experiment. The object of the further research was the samples of the lower jaws stained according to Van Gieson. Histological examination of the bone defect of the experimental group after 1 week showed absence of bone fragments and formation of fibrous callosity in the trauma zone. Further study of regenerate at the 3rd and the 5th weeks showed accelerated bone wound healing in the experimental group (compared to the control group). Thus, the autograft stimulates the process of bone tissue restoration in the area of the defect of the lower jaw model.Vladimir A. UsachevOlga S. ArtashyanVyacheslav V. KotomtsevGleb S. SenkinDaria A. SolosinaScientific Сentre for Family Health and Human Reproduction Problemsarticleregenerationbone tissuefibrous autograftScienceQRUActa Biomedica Scientifica, Vol 4, Iss 1, Pp 162-165 (2019)
institution DOAJ
collection DOAJ
language RU
topic regeneration
bone tissue
fibrous autograft
Science
Q
spellingShingle regeneration
bone tissue
fibrous autograft
Science
Q
Vladimir A. Usachev
Olga S. Artashyan
Vyacheslav V. Kotomtsev
Gleb S. Senkin
Daria A. Solosina
Application of the Fibrous Autograft in Posttraumatic Bone Regeneration of the Lower Jaw
description The search for new types of bone substitutes is one of the topical problems of biology and medicine. The paper considered the role of fibrous autograft in reparative bone regeneration in the rat’s lower jaw model. Thirty Wistar rats were taken in the experiment: 15 in the experimental and 15 in the control group. Fibrous autograft was formed on the cellophane basis under the skin on the back of rats. Injury in the lower jaw with a diameter of 2 mm was formed and a fibrous graft was placed in injuries in the experimental group. Five animals from each groups were sacrificed at the first, third and fifth weeks of the experiment. The object of the further research was the samples of the lower jaws stained according to Van Gieson. Histological examination of the bone defect of the experimental group after 1 week showed absence of bone fragments and formation of fibrous callosity in the trauma zone. Further study of regenerate at the 3rd and the 5th weeks showed accelerated bone wound healing in the experimental group (compared to the control group). Thus, the autograft stimulates the process of bone tissue restoration in the area of the defect of the lower jaw model.
format article
author Vladimir A. Usachev
Olga S. Artashyan
Vyacheslav V. Kotomtsev
Gleb S. Senkin
Daria A. Solosina
author_facet Vladimir A. Usachev
Olga S. Artashyan
Vyacheslav V. Kotomtsev
Gleb S. Senkin
Daria A. Solosina
author_sort Vladimir A. Usachev
title Application of the Fibrous Autograft in Posttraumatic Bone Regeneration of the Lower Jaw
title_short Application of the Fibrous Autograft in Posttraumatic Bone Regeneration of the Lower Jaw
title_full Application of the Fibrous Autograft in Posttraumatic Bone Regeneration of the Lower Jaw
title_fullStr Application of the Fibrous Autograft in Posttraumatic Bone Regeneration of the Lower Jaw
title_full_unstemmed Application of the Fibrous Autograft in Posttraumatic Bone Regeneration of the Lower Jaw
title_sort application of the fibrous autograft in posttraumatic bone regeneration of the lower jaw
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2019
url https://doaj.org/article/e95cec5c858b4199a0a8878c3dfdca40
work_keys_str_mv AT vladimirausachev applicationofthefibrousautograftinposttraumaticboneregenerationofthelowerjaw
AT olgasartashyan applicationofthefibrousautograftinposttraumaticboneregenerationofthelowerjaw
AT vyacheslavvkotomtsev applicationofthefibrousautograftinposttraumaticboneregenerationofthelowerjaw
AT glebssenkin applicationofthefibrousautograftinposttraumaticboneregenerationofthelowerjaw
AT dariaasolosina applicationofthefibrousautograftinposttraumaticboneregenerationofthelowerjaw
_version_ 1718416981920579584