Precise temporal regulation of alternative splicing during neural development

The precise timing of neurodevelopmental splicing switches and the underlying regulatory mechanisms remain poorly understood. This study identifies two major waves of developmental switches under the control of distinct combinations of RNA-binding proteins in central and peripheral nervous systems.

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Autores principales:	Sebastien M. Weyn-Vanhentenryck, Huijuan Feng, Dmytro Ustianenko, Rachel Duffié, Qinghong Yan, Martin Jacko, Jose C. Martinez, Marianne Goodwin, Xuegong Zhang, Ulrich Hengst, Stavros Lomvardas, Maurice S. Swanson, Chaolin Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e95f34f767ed420686c114eb449248ee
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spelling	oai:doaj.org-article:e95f34f767ed420686c114eb449248ee2021-12-02T15:34:48ZPrecise temporal regulation of alternative splicing during neural development10.1038/s41467-018-04559-02041-1723https://doaj.org/article/e95f34f767ed420686c114eb449248ee2018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04559-0https://doaj.org/toc/2041-1723The precise timing of neurodevelopmental splicing switches and the underlying regulatory mechanisms remain poorly understood. This study identifies two major waves of developmental switches under the control of distinct combinations of RNA-binding proteins in central and peripheral nervous systems.Sebastien M. Weyn-VanhentenryckHuijuan FengDmytro UstianenkoRachel DuffiéQinghong YanMartin JackoJose C. MartinezMarianne GoodwinXuegong ZhangUlrich HengstStavros LomvardasMaurice S. SwansonChaolin ZhangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sebastien M. Weyn-Vanhentenryck Huijuan Feng Dmytro Ustianenko Rachel Duffié Qinghong Yan Martin Jacko Jose C. Martinez Marianne Goodwin Xuegong Zhang Ulrich Hengst Stavros Lomvardas Maurice S. Swanson Chaolin Zhang Precise temporal regulation of alternative splicing during neural development
description	The precise timing of neurodevelopmental splicing switches and the underlying regulatory mechanisms remain poorly understood. This study identifies two major waves of developmental switches under the control of distinct combinations of RNA-binding proteins in central and peripheral nervous systems.
format	article
author	Sebastien M. Weyn-Vanhentenryck Huijuan Feng Dmytro Ustianenko Rachel Duffié Qinghong Yan Martin Jacko Jose C. Martinez Marianne Goodwin Xuegong Zhang Ulrich Hengst Stavros Lomvardas Maurice S. Swanson Chaolin Zhang
author_facet	Sebastien M. Weyn-Vanhentenryck Huijuan Feng Dmytro Ustianenko Rachel Duffié Qinghong Yan Martin Jacko Jose C. Martinez Marianne Goodwin Xuegong Zhang Ulrich Hengst Stavros Lomvardas Maurice S. Swanson Chaolin Zhang
author_sort	Sebastien M. Weyn-Vanhentenryck
title	Precise temporal regulation of alternative splicing during neural development
title_short	Precise temporal regulation of alternative splicing during neural development
title_full	Precise temporal regulation of alternative splicing during neural development
title_fullStr	Precise temporal regulation of alternative splicing during neural development
title_full_unstemmed	Precise temporal regulation of alternative splicing during neural development
title_sort	precise temporal regulation of alternative splicing during neural development
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e95f34f767ed420686c114eb449248ee
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Precise temporal regulation of alternative splicing during neural development

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