Disseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent

Abstract Background Splenectomized patients are at an increased risk for overwhelming post-splenectomy infections typically with encapsulated bacteria. The clinical association between splenectomy and lymph-node tuberculosis is unclear. Case presentation We describe a rare case of disseminated tuber...

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Autores principales:	Moxin Cheng, Yu Chen
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Adolescent Splenectomy Disseminated tuberculous lymphadenitis Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/e9616d3c28ad4ac88715640548ad5535
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spelling	oai:doaj.org-article:e9616d3c28ad4ac88715640548ad55352021-11-28T12:41:59ZDisseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent10.1186/s12879-021-06859-11471-2334https://doaj.org/article/e9616d3c28ad4ac88715640548ad55352021-11-01T00:00:00Zhttps://doi.org/10.1186/s12879-021-06859-1https://doaj.org/toc/1471-2334Abstract Background Splenectomized patients are at an increased risk for overwhelming post-splenectomy infections typically with encapsulated bacteria. The clinical association between splenectomy and lymph-node tuberculosis is unclear. Case presentation We describe a rare case of disseminated tuberculous lymphadenitis in an 18-year-old woman with history of splenectomy because of hereditary sherocytosis. She was admitted with enlargement of bilateral-cervical and left-axillary lymph nodes and fever. A diagnosis of probable tuberculosis was made based on the findings of fine-needle aspiration. Histology showed granulomas and extensive caseous necrosis, with the site of puncture located at an enlarged lymph node on the right side. The diagnosis was confirmed via nucleic-acid amplification tests following excisional biopsy of the left axillary lymph node. Disseminated tuberculous lymphadenitis was localized in the bilateral neck, right lung hilum, left sub-axillary region, and mediastinum, as detected from contrast-enhanced computed tomography of the neck. Conclusions Mycobacterium tuberculosis infection should be considered in children and adolescents with extensive enlargement of lymph nodes after splenectomy.Moxin ChengYu ChenBMCarticleAdolescentSplenectomyDisseminated tuberculous lymphadenitisInfectious and parasitic diseasesRC109-216ENBMC Infectious Diseases, Vol 21, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Adolescent Splenectomy Disseminated tuberculous lymphadenitis Infectious and parasitic diseases RC109-216
spellingShingle	Adolescent Splenectomy Disseminated tuberculous lymphadenitis Infectious and parasitic diseases RC109-216 Moxin Cheng Yu Chen Disseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent
description	Abstract Background Splenectomized patients are at an increased risk for overwhelming post-splenectomy infections typically with encapsulated bacteria. The clinical association between splenectomy and lymph-node tuberculosis is unclear. Case presentation We describe a rare case of disseminated tuberculous lymphadenitis in an 18-year-old woman with history of splenectomy because of hereditary sherocytosis. She was admitted with enlargement of bilateral-cervical and left-axillary lymph nodes and fever. A diagnosis of probable tuberculosis was made based on the findings of fine-needle aspiration. Histology showed granulomas and extensive caseous necrosis, with the site of puncture located at an enlarged lymph node on the right side. The diagnosis was confirmed via nucleic-acid amplification tests following excisional biopsy of the left axillary lymph node. Disseminated tuberculous lymphadenitis was localized in the bilateral neck, right lung hilum, left sub-axillary region, and mediastinum, as detected from contrast-enhanced computed tomography of the neck. Conclusions Mycobacterium tuberculosis infection should be considered in children and adolescents with extensive enlargement of lymph nodes after splenectomy.
format	article
author	Moxin Cheng Yu Chen
author_facet	Moxin Cheng Yu Chen
author_sort	Moxin Cheng
title	Disseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent
title_short	Disseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent
title_full	Disseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent
title_fullStr	Disseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent
title_full_unstemmed	Disseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent
title_sort	disseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent
publisher	BMC
publishDate	2021
url	https://doaj.org/article/e9616d3c28ad4ac88715640548ad5535
work_keys_str_mv	AT moxincheng disseminatedlymphnodetuberculosisaftersplenectomyanunusualcasereportinanadolescent AT yuchen disseminatedlymphnodetuberculosisaftersplenectomyanunusualcasereportinanadolescent
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Disseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent

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