TwinCons: Conservation score for uncovering deep sequence similarity and divergence

We have developed the program TwinCons, to detect noisy signals of deep ancestry of proteins or nucleic acids. As input, the program uses a composite alignment containing pre-defined groups, and mathematically determines a ‘cost’ of transforming one group to the other at each position of the alignme...

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Autores principales: Petar I. Penev, Claudia Alvarez-Carreño, Eric Smith, Anton S. Petrov, Loren Dean Williams
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/e964b131d31148a489815dceb4e20530
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