BLOOD LEVELS OF INTERLEUKIN-6 AND INTERLEUKIN-10 IN SERUM AND BIOMARKERS OF ACUTE KIDNEY INJURY IN ACUTE CORONARY SYNDROME

Certain correlations between changes of cytokine levels and kidney dysfunction, as well as their prognostic significance for development of acute kidney injury (АКI) in different clinical forms of ischemic heart disease (IHD) seem to be worth of further studies. The levels of IL-6 and IL-10 and thei...

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Autores principales:	M. A. Shalenkova, Z. D. Mikhailova, P. F. Klimkin, E. T. Manyukova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2015
Materias:	interleukins creatinine neutrophil gelatinase-associated lipocalin (ngal) acute coronary syndrome acute kidney injury Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/e9749093e88a4d879b383968a1e8441a
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id	oai:doaj.org-article:e9749093e88a4d879b383968a1e8441a
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spelling	oai:doaj.org-article:e9749093e88a4d879b383968a1e8441a2021-11-18T08:03:44ZBLOOD LEVELS OF INTERLEUKIN-6 AND INTERLEUKIN-10 IN SERUM AND BIOMARKERS OF ACUTE KIDNEY INJURY IN ACUTE CORONARY SYNDROME1563-06252313-741X10.15789/1563-0625-2015-1-47-52https://doaj.org/article/e9749093e88a4d879b383968a1e8441a2015-03-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/807https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XCertain correlations between changes of cytokine levels and kidney dysfunction, as well as their prognostic significance for development of acute kidney injury (АКI) in different clinical forms of ischemic heart disease (IHD) seem to be worth of further studies. The levels of IL-6 and IL-10 and their correlation with serum creatinine (sCr) and lipocalin levels in urine (u-NGAL) were studied in 98 IHD patients, of them 93 presented with acute coronary syndrome (ACS) and 5, with stable angina pectoris. ACS patients were found to have increased levels of IL-6, IL-10, sCr, u-NGAL. IL-6 and IL-10 contents proved to be increased in cases of non-ST-segment elevation ACS (NSTE-ACS), and during AKI development. According to serum creatinin levels, AKI was more frequently revealed in patients with NSTE-ACS. Urinary NGAL levels were found to be higher in ACS with ST segment elevation.M. A. ShalenkovaZ. D. MikhailovaP. F. KlimkinE. T. ManyukovaSPb RAACIarticleinterleukinscreatinineneutrophil gelatinase-associated lipocalin (ngal)acute coronary syndromeacute kidney injuryImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 17, Iss 1, Pp 47-52 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	interleukins creatinine neutrophil gelatinase-associated lipocalin (ngal) acute coronary syndrome acute kidney injury Immunologic diseases. Allergy RC581-607
spellingShingle	interleukins creatinine neutrophil gelatinase-associated lipocalin (ngal) acute coronary syndrome acute kidney injury Immunologic diseases. Allergy RC581-607 M. A. Shalenkova Z. D. Mikhailova P. F. Klimkin E. T. Manyukova BLOOD LEVELS OF INTERLEUKIN-6 AND INTERLEUKIN-10 IN SERUM AND BIOMARKERS OF ACUTE KIDNEY INJURY IN ACUTE CORONARY SYNDROME
description	Certain correlations between changes of cytokine levels and kidney dysfunction, as well as their prognostic significance for development of acute kidney injury (АКI) in different clinical forms of ischemic heart disease (IHD) seem to be worth of further studies. The levels of IL-6 and IL-10 and their correlation with serum creatinine (sCr) and lipocalin levels in urine (u-NGAL) were studied in 98 IHD patients, of them 93 presented with acute coronary syndrome (ACS) and 5, with stable angina pectoris. ACS patients were found to have increased levels of IL-6, IL-10, sCr, u-NGAL. IL-6 and IL-10 contents proved to be increased in cases of non-ST-segment elevation ACS (NSTE-ACS), and during AKI development. According to serum creatinin levels, AKI was more frequently revealed in patients with NSTE-ACS. Urinary NGAL levels were found to be higher in ACS with ST segment elevation.
format	article
author	M. A. Shalenkova Z. D. Mikhailova P. F. Klimkin E. T. Manyukova
author_facet	M. A. Shalenkova Z. D. Mikhailova P. F. Klimkin E. T. Manyukova
author_sort	M. A. Shalenkova
title	BLOOD LEVELS OF INTERLEUKIN-6 AND INTERLEUKIN-10 IN SERUM AND BIOMARKERS OF ACUTE KIDNEY INJURY IN ACUTE CORONARY SYNDROME
title_short	BLOOD LEVELS OF INTERLEUKIN-6 AND INTERLEUKIN-10 IN SERUM AND BIOMARKERS OF ACUTE KIDNEY INJURY IN ACUTE CORONARY SYNDROME
title_full	BLOOD LEVELS OF INTERLEUKIN-6 AND INTERLEUKIN-10 IN SERUM AND BIOMARKERS OF ACUTE KIDNEY INJURY IN ACUTE CORONARY SYNDROME
title_fullStr	BLOOD LEVELS OF INTERLEUKIN-6 AND INTERLEUKIN-10 IN SERUM AND BIOMARKERS OF ACUTE KIDNEY INJURY IN ACUTE CORONARY SYNDROME
title_full_unstemmed	BLOOD LEVELS OF INTERLEUKIN-6 AND INTERLEUKIN-10 IN SERUM AND BIOMARKERS OF ACUTE KIDNEY INJURY IN ACUTE CORONARY SYNDROME
title_sort	blood levels of interleukin-6 and interleukin-10 in serum and biomarkers of acute kidney injury in acute coronary syndrome
publisher	SPb RAACI
publishDate	2015
url	https://doaj.org/article/e9749093e88a4d879b383968a1e8441a
work_keys_str_mv	AT mashalenkova bloodlevelsofinterleukin6andinterleukin10inserumandbiomarkersofacutekidneyinjuryinacutecoronarysyndrome AT zdmikhailova bloodlevelsofinterleukin6andinterleukin10inserumandbiomarkersofacutekidneyinjuryinacutecoronarysyndrome AT pfklimkin bloodlevelsofinterleukin6andinterleukin10inserumandbiomarkersofacutekidneyinjuryinacutecoronarysyndrome AT etmanyukova bloodlevelsofinterleukin6andinterleukin10inserumandbiomarkersofacutekidneyinjuryinacutecoronarysyndrome
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BLOOD LEVELS OF INTERLEUKIN-6 AND INTERLEUKIN-10 IN SERUM AND BIOMARKERS OF ACUTE KIDNEY INJURY IN ACUTE CORONARY SYNDROME

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