Defects in innate immunity render breast cancer initiating cells permissive to oncolytic adenovirus.

Defects in innate immunity render breast cancer initiating cells permissive to oncolytic adenovirus.

<h4>Background</h4>Cancer stem cells/initiating cells (CSC/CIC), are thought to exist as a small population in malignant tissues. They are resistant to conventional cancer treatments and possibly underlie post-treatment relapse. The CIC population can be targeted with capsid modified onc...

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Autores principales: Laura Ahtiainen, Cristina Mirantes, Tiina Jahkola, Sophie Escutenaire, Iulia Diaconu, Pamela Osterlund, Anna Kanerva, Vincenzo Cerullo, Akseli Hemminki
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/e980cd7d5ead401aa6fc1c566dc14e69
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