Defects in innate immunity render breast cancer initiating cells permissive to oncolytic adenovirus.
<h4>Background</h4>Cancer stem cells/initiating cells (CSC/CIC), are thought to exist as a small population in malignant tissues. They are resistant to conventional cancer treatments and possibly underlie post-treatment relapse. The CIC population can be targeted with capsid modified onc...
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Auteurs principaux: | Laura Ahtiainen, Cristina Mirantes, Tiina Jahkola, Sophie Escutenaire, Iulia Diaconu, Pamela Osterlund, Anna Kanerva, Vincenzo Cerullo, Akseli Hemminki |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2010
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Sujets: | |
Accès en ligne: | https://doaj.org/article/e980cd7d5ead401aa6fc1c566dc14e69 |
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