Local dimensionality determines imaging speed in localization microscopy

Localisation microscopy enables nanometre-scale imaging of biological samples, but the method is too slow to use on dynamic systems. Here, the authors develop a mathematical model that optimises the number of frames required and estimates the maximum speed for super-resolution imaging.

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Autores principales: Patrick Fox-Roberts, Richard Marsh, Karin Pfisterer, Asier Jayo, Maddy Parsons, Susan Cox
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e984f0423c1e4fbda3a2068a71ae849a
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spelling oai:doaj.org-article:e984f0423c1e4fbda3a2068a71ae849a2021-12-02T15:38:49ZLocal dimensionality determines imaging speed in localization microscopy10.1038/ncomms135582041-1723https://doaj.org/article/e984f0423c1e4fbda3a2068a71ae849a2017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms13558https://doaj.org/toc/2041-1723Localisation microscopy enables nanometre-scale imaging of biological samples, but the method is too slow to use on dynamic systems. Here, the authors develop a mathematical model that optimises the number of frames required and estimates the maximum speed for super-resolution imaging.Patrick Fox-RobertsRichard MarshKarin PfistererAsier JayoMaddy ParsonsSusan CoxNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Patrick Fox-Roberts
Richard Marsh
Karin Pfisterer
Asier Jayo
Maddy Parsons
Susan Cox
Local dimensionality determines imaging speed in localization microscopy
description Localisation microscopy enables nanometre-scale imaging of biological samples, but the method is too slow to use on dynamic systems. Here, the authors develop a mathematical model that optimises the number of frames required and estimates the maximum speed for super-resolution imaging.
format article
author Patrick Fox-Roberts
Richard Marsh
Karin Pfisterer
Asier Jayo
Maddy Parsons
Susan Cox
author_facet Patrick Fox-Roberts
Richard Marsh
Karin Pfisterer
Asier Jayo
Maddy Parsons
Susan Cox
author_sort Patrick Fox-Roberts
title Local dimensionality determines imaging speed in localization microscopy
title_short Local dimensionality determines imaging speed in localization microscopy
title_full Local dimensionality determines imaging speed in localization microscopy
title_fullStr Local dimensionality determines imaging speed in localization microscopy
title_full_unstemmed Local dimensionality determines imaging speed in localization microscopy
title_sort local dimensionality determines imaging speed in localization microscopy
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/e984f0423c1e4fbda3a2068a71ae849a
work_keys_str_mv AT patrickfoxroberts localdimensionalitydeterminesimagingspeedinlocalizationmicroscopy
AT richardmarsh localdimensionalitydeterminesimagingspeedinlocalizationmicroscopy
AT karinpfisterer localdimensionalitydeterminesimagingspeedinlocalizationmicroscopy
AT asierjayo localdimensionalitydeterminesimagingspeedinlocalizationmicroscopy
AT maddyparsons localdimensionalitydeterminesimagingspeedinlocalizationmicroscopy
AT susancox localdimensionalitydeterminesimagingspeedinlocalizationmicroscopy
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