Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism

Pu-erh tea displays cholesterol-lowering properties. Here, Huang et al. show that this is mostly due to the action of a pigment in Pu-erh tea that induces changes in certain gut microbiota and bile acid levels, thus modulating the gut-liver metabolic axis.

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Autores principales: Fengjie Huang, Xiaojiao Zheng, Xiaohui Ma, Runqiu Jiang, Wangyi Zhou, Shuiping Zhou, Yunjing Zhang, Sha Lei, Shouli Wang, Junliang Kuang, Xiaolong Han, Meilin Wei, Yijun You, Mengci Li, Yitao Li, Dandan Liang, Jiajian Liu, Tianlu Chen, Chao Yan, Runmin Wei, Cynthia Rajani, Chengxing Shen, Guoxiang Xie, Zhaoxiang Bian, Houkai Li, Aihua Zhao, Wei Jia
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e98a12c3666947a7a7f653b46b316205
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spelling oai:doaj.org-article:e98a12c3666947a7a7f653b46b3162052021-12-02T14:39:41ZTheabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism10.1038/s41467-019-12896-x2041-1723https://doaj.org/article/e98a12c3666947a7a7f653b46b3162052019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12896-xhttps://doaj.org/toc/2041-1723Pu-erh tea displays cholesterol-lowering properties. Here, Huang et al. show that this is mostly due to the action of a pigment in Pu-erh tea that induces changes in certain gut microbiota and bile acid levels, thus modulating the gut-liver metabolic axis.Fengjie HuangXiaojiao ZhengXiaohui MaRunqiu JiangWangyi ZhouShuiping ZhouYunjing ZhangSha LeiShouli WangJunliang KuangXiaolong HanMeilin WeiYijun YouMengci LiYitao LiDandan LiangJiajian LiuTianlu ChenChao YanRunmin WeiCynthia RajaniChengxing ShenGuoxiang XieZhaoxiang BianHoukai LiAihua ZhaoWei JiaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Fengjie Huang
Xiaojiao Zheng
Xiaohui Ma
Runqiu Jiang
Wangyi Zhou
Shuiping Zhou
Yunjing Zhang
Sha Lei
Shouli Wang
Junliang Kuang
Xiaolong Han
Meilin Wei
Yijun You
Mengci Li
Yitao Li
Dandan Liang
Jiajian Liu
Tianlu Chen
Chao Yan
Runmin Wei
Cynthia Rajani
Chengxing Shen
Guoxiang Xie
Zhaoxiang Bian
Houkai Li
Aihua Zhao
Wei Jia
Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
description Pu-erh tea displays cholesterol-lowering properties. Here, Huang et al. show that this is mostly due to the action of a pigment in Pu-erh tea that induces changes in certain gut microbiota and bile acid levels, thus modulating the gut-liver metabolic axis.
format article
author Fengjie Huang
Xiaojiao Zheng
Xiaohui Ma
Runqiu Jiang
Wangyi Zhou
Shuiping Zhou
Yunjing Zhang
Sha Lei
Shouli Wang
Junliang Kuang
Xiaolong Han
Meilin Wei
Yijun You
Mengci Li
Yitao Li
Dandan Liang
Jiajian Liu
Tianlu Chen
Chao Yan
Runmin Wei
Cynthia Rajani
Chengxing Shen
Guoxiang Xie
Zhaoxiang Bian
Houkai Li
Aihua Zhao
Wei Jia
author_facet Fengjie Huang
Xiaojiao Zheng
Xiaohui Ma
Runqiu Jiang
Wangyi Zhou
Shuiping Zhou
Yunjing Zhang
Sha Lei
Shouli Wang
Junliang Kuang
Xiaolong Han
Meilin Wei
Yijun You
Mengci Li
Yitao Li
Dandan Liang
Jiajian Liu
Tianlu Chen
Chao Yan
Runmin Wei
Cynthia Rajani
Chengxing Shen
Guoxiang Xie
Zhaoxiang Bian
Houkai Li
Aihua Zhao
Wei Jia
author_sort Fengjie Huang
title Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
title_short Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
title_full Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
title_fullStr Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
title_full_unstemmed Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
title_sort theabrownin from pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e98a12c3666947a7a7f653b46b316205
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