Incidence of Cyp51 A key mutations in Aspergillus fumigatus-a study on primary clinical samples of immunocompromised patients in the period of 1995-2013.

Incidence of Cyp51 A key mutations in Aspergillus fumigatus-a study on primary clinical samples of immunocompromised patients in the period of 1995-2013.

As the incidence of azole resistance in Aspergillus fumigatus is rising and the diagnosis of invasive aspergillosis (IA) in immunocompromised patients is rarely based on positive culture yield, we screened our Aspergillus DNA sample collection for the occurrence of azole resistance mediating cyp51 A...

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Main Authors: Birgit Spiess, Patricia Postina, Mark Reinwald, Oliver A Cornely, Axel Hamprecht, Martin Hoenigl, Cornelia Lass-Flörl, Peter-Michael Rath, Jörg Steinmann, Thomas Miethke, Melchior Lauten, Silke Will, Natalia Merker, Wolf-Karsten Hofmann, Dieter Buchheidt
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e99678bdea7548a8b743e8a48bca6a76
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