Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria

Insertion sequences (IS) are common mobile genetic elements in bacteria, but their effects on bacterial evolution are not well understood. Here, Consuegra and colleagues investigate the dynamics and fitness consequences of IS elements in E. coli over 50,000 generations.

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Autores principales: Jessika Consuegra, Joël Gaffé, Richard E. Lenski, Thomas Hindré, Jeffrey E. Barrick, Olivier Tenaillon, Dominique Schneider
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e996c6b3661a4328bd3da865b5d3e48a
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spelling oai:doaj.org-article:e996c6b3661a4328bd3da865b5d3e48a2021-12-02T14:26:44ZInsertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria10.1038/s41467-021-21210-72041-1723https://doaj.org/article/e996c6b3661a4328bd3da865b5d3e48a2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21210-7https://doaj.org/toc/2041-1723Insertion sequences (IS) are common mobile genetic elements in bacteria, but their effects on bacterial evolution are not well understood. Here, Consuegra and colleagues investigate the dynamics and fitness consequences of IS elements in E. coli over 50,000 generations.Jessika ConsuegraJoël GafféRichard E. LenskiThomas HindréJeffrey E. BarrickOlivier TenaillonDominique SchneiderNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jessika Consuegra
Joël Gaffé
Richard E. Lenski
Thomas Hindré
Jeffrey E. Barrick
Olivier Tenaillon
Dominique Schneider
Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
description Insertion sequences (IS) are common mobile genetic elements in bacteria, but their effects on bacterial evolution are not well understood. Here, Consuegra and colleagues investigate the dynamics and fitness consequences of IS elements in E. coli over 50,000 generations.
format article
author Jessika Consuegra
Joël Gaffé
Richard E. Lenski
Thomas Hindré
Jeffrey E. Barrick
Olivier Tenaillon
Dominique Schneider
author_facet Jessika Consuegra
Joël Gaffé
Richard E. Lenski
Thomas Hindré
Jeffrey E. Barrick
Olivier Tenaillon
Dominique Schneider
author_sort Jessika Consuegra
title Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
title_short Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
title_full Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
title_fullStr Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
title_full_unstemmed Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
title_sort insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e996c6b3661a4328bd3da865b5d3e48a
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