Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria

Insertion sequences (IS) are common mobile genetic elements in bacteria, but their effects on bacterial evolution are not well understood. Here, Consuegra and colleagues investigate the dynamics and fitness consequences of IS elements in E. coli over 50,000 generations.

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Jessika Consuegra, Joël Gaffé, Richard E. Lenski, Thomas Hindré, Jeffrey E. Barrick, Olivier Tenaillon, Dominique Schneider
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/e996c6b3661a4328bd3da865b5d3e48a
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

id	oai:doaj.org-article:e996c6b3661a4328bd3da865b5d3e48a
record_format	dspace
spelling	oai:doaj.org-article:e996c6b3661a4328bd3da865b5d3e48a2021-12-02T14:26:44ZInsertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria10.1038/s41467-021-21210-72041-1723https://doaj.org/article/e996c6b3661a4328bd3da865b5d3e48a2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21210-7https://doaj.org/toc/2041-1723Insertion sequences (IS) are common mobile genetic elements in bacteria, but their effects on bacterial evolution are not well understood. Here, Consuegra and colleagues investigate the dynamics and fitness consequences of IS elements in E. coli over 50,000 generations.Jessika ConsuegraJoël GafféRichard E. LenskiThomas HindréJeffrey E. BarrickOlivier TenaillonDominique SchneiderNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jessika Consuegra Joël Gaffé Richard E. Lenski Thomas Hindré Jeffrey E. Barrick Olivier Tenaillon Dominique Schneider Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
description	Insertion sequences (IS) are common mobile genetic elements in bacteria, but their effects on bacterial evolution are not well understood. Here, Consuegra and colleagues investigate the dynamics and fitness consequences of IS elements in E. coli over 50,000 generations.
format	article
author	Jessika Consuegra Joël Gaffé Richard E. Lenski Thomas Hindré Jeffrey E. Barrick Olivier Tenaillon Dominique Schneider
author_facet	Jessika Consuegra Joël Gaffé Richard E. Lenski Thomas Hindré Jeffrey E. Barrick Olivier Tenaillon Dominique Schneider
author_sort	Jessika Consuegra
title	Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
title_short	Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
title_full	Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
title_fullStr	Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
title_full_unstemmed	Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
title_sort	insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e996c6b3661a4328bd3da865b5d3e48a
work_keys_str_mv	AT jessikaconsuegra insertionsequencemediatedmutationsbothpromoteandconstrainevolvabilityduringalongtermexperimentwithbacteria AT joelgaffe insertionsequencemediatedmutationsbothpromoteandconstrainevolvabilityduringalongtermexperimentwithbacteria AT richardelenski insertionsequencemediatedmutationsbothpromoteandconstrainevolvabilityduringalongtermexperimentwithbacteria AT thomashindre insertionsequencemediatedmutationsbothpromoteandconstrainevolvabilityduringalongtermexperimentwithbacteria AT jeffreyebarrick insertionsequencemediatedmutationsbothpromoteandconstrainevolvabilityduringalongtermexperimentwithbacteria AT oliviertenaillon insertionsequencemediatedmutationsbothpromoteandconstrainevolvabilityduringalongtermexperimentwithbacteria AT dominiqueschneider insertionsequencemediatedmutationsbothpromoteandconstrainevolvabilityduringalongtermexperimentwithbacteria
_version_	1718391343985721344

Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria

Documents similaires