Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria

Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria

Insertion sequences (IS) are common mobile genetic elements in bacteria, but their effects on bacterial evolution are not well understood. Here, Consuegra and colleagues investigate the dynamics and fitness consequences of IS elements in E. coli over 50,000 generations.

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Autores principales: Jessika Consuegra, Joël Gaffé, Richard E. Lenski, Thomas Hindré, Jeffrey E. Barrick, Olivier Tenaillon, Dominique Schneider
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/e996c6b3661a4328bd3da865b5d3e48a
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