Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice.
Light influences sleep and alertness either indirectly through a well-characterized circadian pathway or directly through yet poorly understood mechanisms. Melanopsin (Opn4) is a retinal photopigment crucial for conveying nonvisual light information to the brain. Through extensive characterization o...
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Autores principales: | Jessica W Tsai, Jens Hannibal, Grace Hagiwara, Damien Colas, Elisabeth Ruppert, Norman F Ruby, H Craig Heller, Paul Franken, Patrice Bourgin |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2009
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Materias: | |
Acceso en línea: | https://doaj.org/article/e99f480dd1e8416390caddee6237b1f4 |
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