Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4
Semaphorin-4A is a cell surface protein with known functions in neural development and immune regulation, but the mechanism for immune modulation is unclear. Here the authors show that ILT-4, previously found on myeloid cells, is the receptor of Semaphorin-4A on activate human CD4 T cells for mediat...
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Autores principales: | Ning Lu, Ying Li, Zhiqiang Zhang, Junji Xing, Ying Sun, Sheng Yao, Lieping Chen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/e9a07f42fb3e4178acef5acb85afb605 |
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