Hydrodynamic Clustering of Human Sperm in Viscoelastic Fluids

Abstract We have numerically investigated sperm clustering behaviours, modelling cells as superpositions of regularised flow singularities, coarse-grained from experimentally obtained digital microscopy of human sperm, both in watery medium and a highly viscous–weakly elastic, methylcellulose medium...

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Autores principales:	Kenta Ishimoto, Eamonn A. Gaffney
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Sperm Clusters Linear Maxwell Fluid Flagellum Beats Full Temporal Resolution Angular Autocorrelation Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e9a3a09029894996b5ce36a92df5007e
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spelling	oai:doaj.org-article:e9a3a09029894996b5ce36a92df5007e2021-12-02T15:08:35ZHydrodynamic Clustering of Human Sperm in Viscoelastic Fluids10.1038/s41598-018-33584-82045-2322https://doaj.org/article/e9a3a09029894996b5ce36a92df5007e2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-33584-8https://doaj.org/toc/2045-2322Abstract We have numerically investigated sperm clustering behaviours, modelling cells as superpositions of regularised flow singularities, coarse-grained from experimentally obtained digital microscopy of human sperm, both in watery medium and a highly viscous–weakly elastic, methylcellulose medium. We find that the cell yaw and cell pulling dynamics inhibit clustering in low viscosity media. In contrast clustering is readily visible in simulations modelling sperm within a methylcellulose medium, in line with previous observations that bovine sperm clustering is much more prominent in a rheological polyacrylamide medium. Furthermore, the fine-scale details of sperm flagellar movement substantially impact large-scale collective behaviours, further motivating the need for the digital microscopy and characterization of sperm to understand their dynamics.Kenta IshimotoEamonn A. GaffneyNature PortfolioarticleSperm ClustersLinear Maxwell FluidFlagellum BeatsFull Temporal ResolutionAngular AutocorrelationMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Sperm Clusters Linear Maxwell Fluid Flagellum Beats Full Temporal Resolution Angular Autocorrelation Medicine R Science Q
spellingShingle	Sperm Clusters Linear Maxwell Fluid Flagellum Beats Full Temporal Resolution Angular Autocorrelation Medicine R Science Q Kenta Ishimoto Eamonn A. Gaffney Hydrodynamic Clustering of Human Sperm in Viscoelastic Fluids
description	Abstract We have numerically investigated sperm clustering behaviours, modelling cells as superpositions of regularised flow singularities, coarse-grained from experimentally obtained digital microscopy of human sperm, both in watery medium and a highly viscous–weakly elastic, methylcellulose medium. We find that the cell yaw and cell pulling dynamics inhibit clustering in low viscosity media. In contrast clustering is readily visible in simulations modelling sperm within a methylcellulose medium, in line with previous observations that bovine sperm clustering is much more prominent in a rheological polyacrylamide medium. Furthermore, the fine-scale details of sperm flagellar movement substantially impact large-scale collective behaviours, further motivating the need for the digital microscopy and characterization of sperm to understand their dynamics.
format	article
author	Kenta Ishimoto Eamonn A. Gaffney
author_facet	Kenta Ishimoto Eamonn A. Gaffney
author_sort	Kenta Ishimoto
title	Hydrodynamic Clustering of Human Sperm in Viscoelastic Fluids
title_short	Hydrodynamic Clustering of Human Sperm in Viscoelastic Fluids
title_full	Hydrodynamic Clustering of Human Sperm in Viscoelastic Fluids
title_fullStr	Hydrodynamic Clustering of Human Sperm in Viscoelastic Fluids
title_full_unstemmed	Hydrodynamic Clustering of Human Sperm in Viscoelastic Fluids
title_sort	hydrodynamic clustering of human sperm in viscoelastic fluids
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e9a3a09029894996b5ce36a92df5007e
work_keys_str_mv	AT kentaishimoto hydrodynamicclusteringofhumansperminviscoelasticfluids AT eamonnagaffney hydrodynamicclusteringofhumansperminviscoelasticfluids
_version_	1718388096789118976

Hydrodynamic Clustering of Human Sperm in Viscoelastic Fluids

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